Protein Information

Name BMP2
Synonyms BMP 2; BMP 2A; BMP2; BMP2A; Bone morphogenetic protein 2 precursor; bone morphogenetic protein 2; Bone morphogenetic protein 2 precursors; bone morphogenetic protein 2s

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
15614776 Peiffer DA, Von Bubnoff A, Shin Y, Kitayama A, Mochii M, Ueno N, Cho KW: A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development. Dev Dyn. 2005 Feb;232(2):445-56.

To identify target genes regulated by the BMP growth factor family in Xenopus, large-scale microarray analyses were conducted to discover genes directly activated by this factor in dissociated animal cap tissues treated with a combination of the protein synthesis inhibitor cycloheximide and BMP2.
32(0,1,1,2) Details
16835229 Fukui N, Ikeda Y, Ohnuki T, Hikita A, Tanaka S, Yamane S, Suzuki R, Sandell LJ, Ochi T: Pro-inflammatory cytokine tumor necrosis factor-alpha induces bone morphogenetic protein-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation. J Biol Chem. 2006 Sep 15;281(37):27229-41. Epub 2006 Jul 11.

The results of nuclear run-off assay and cycloheximide treatment consistently indicated that ATDC5 cells acquire the capacity to synthesize BMP-2 mRNA in the nuclei during the differentiation process.
2(0,0,0,2) Details
17113042 Hsu YL, Chang JK, Tsai CH, Chien TT, Kuo PL: Myricetin induces human osteoblast differentiation through bone morphogenetic protein-2/p38 mitogen-activated protein kinase pathway. Biochem Pharmacol. 2007 Feb 15;73(4):504-14. Epub 2006 Oct 26.

2(0,0,0,2) Details