Protein Information

Name IGF2
Synonyms IGF 2; IGF II; IGF2; INSIGF; Insulin like growth factor II; Insulin like growth factor II precursor; Putative insulin like growth factor II associated protein…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
17082775 Chen HL, Li T, Qiu XW, Wu J, Ling JQ, Sun ZH, Wang W, Chen W, Hou A, Vu TH, Hoffman AR, Hu JF: Correction of aberrant imprinting of IGF2 in human tumors by nuclear transfer-induced epigenetic reprogramming. EMBO J. 2006 Nov 15;25(22):5329-38. Epub 2006 Nov 2.

Inhibition of the synthesis of putative trans imprinting factors with cycloheximide led to loss of IGF2 imprinting in normal cultured fibroblasts, suggesting that normal cells produce proteins that act in trans to induce or maintain genomic imprinting.
36(0,1,1,6) Details