| Name | ALAS |
|---|---|
| Synonyms | 5 aminolevulinic acid synthase; ALAS; ALAS 1; ALAS 3; ALAS H; ALAS1; ALAS3; ALASH… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15763493 | Kaliman PA, Barannik T, Strel'chenko E, Inshina N, Sokol O: Intracellular redistribution of heme in rat liver under oxidative stress: the role of heme synthesis. Cell Biol Int. 2005 Jan;29(1):9-14. Epub 2005 Jan 26. Membrane stabilisation by or prevention of early ALAS induction by cycloheximide prevented both mitochondrial heme accumulation and increase of TDO heme saturation. |
7(0,0,1,2) | Details |
| 18719978 | Zheng J, Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL: Differential regulation of human ALAS1 mRNA and protein levels by heme and Mol Cell Biochem. 2008 Dec;319(1-2):153-61. Epub 2008 Aug 22. Measurement of protein in the presence of cycloheximide (CHX) suggests that elevation of the precursor form is due to the increase in protein half-lives. |
6(0,0,0,6) | Details |
| 16234850 | Abu-Farha M, Niles J, Willmore WG: Erythroid-specific synthase protein is stabilized by low and proteasomal inhibition. Biochem Cell Biol. 2005 Oct;83(5):620-30. synthase (ALAS; E.C. 2.3.1.37) catalyzes the first and rate-limiting step of heme synthesis within the mitochondria. We examined protein turnover of ALAS2 in the presence of cycloheximide in K562 cells. |
3(0,0,0,3) | Details |