Protein Information

Name protein C
Synonyms A1 activator; PSAP; Protein C; CSAct; Cerebroside sulfatase activator; Cerebroside sulfate activator; Co beta glucosidase; Component C…

Compound Information

Name copper sulfate
CAS sulfuric acid copper(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
12926769 Roeber DL, Belk KE, Engle TE, Field TG, Koontz SR, Scanga JA, Tatum JD, Mason GL, Van Metre D, Garry FB, Smith GC: The effect of vitamin E supplementation on discoloration of injection-site lesions in retail cuts and the greening reaction observed in injection-site lesions in muscles of the chuck. J Anim Sci. 2003 Aug;81(8):1885-94.

Normal muscle tissue displayed a 3.2 and 56.7% decrease in absorbance/microg of protein as wavelength changed from 654 to 656 nm and 656 to 658 nm, respectively.
In Phase I of Exp. 3, pigments extracted from green lesions obtained from Exp. 2 were compared with solutions, exposed to a high partial pressure of oxygen (ppO), of myoglobin (Mb), copper sulfate, hydrogen peroxide (H2O2), vaccine, and aluminum hydroxide either alone or in combination.
2(0,0,0,2) Details
6965944 Lipsky PE, Ziff M: Inhibition of human helper T cell function in vitro by D-penicillamine and CuSO4. J Clin Invest. 1980 May;65(5):1069-76.

The effect of d-penicillamine (Pen) and mixtures of Pen and copper sulfate on the capacity of normal human peripheral blood mononuclear cells (PBM) to generate immunoglobulin-secreting cells (ISC) in response to the T-cell-dependent polyclonal B-cell activators pokeweed mitogen (PWM) and staphylococcal protein A (SPA) was examined.
81(1,1,1,1) Details
8760927 Yoneyama H, Nakae T: Protein C (OprC) of the outer membrane of Pseudomonas aeruginosa is a copper-regulated channel protein. Microbiology. 1996 Aug;142 ( Pt 8):2137-44.

2(0,0,0,2) Details
8376590 Nishinaga M, Ozawa T, Shimada K: Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest. 1993 Sep;92(3):1381-6.


Previous studies showed that homocysteine, a thrombo-atherogenic and atherogenic agent, inhibits an endothelial thrombomodulin-protein C anticoagulant pathway.
1(0,0,0,1) Details
3400233 Gorbatov VA: [A modified method of determining the level of total protein as a screening test] Vrach Delo. 1988 Apr;(4):82-3.

1(0,0,0,1) Details
3435476 Dameron CT, Harris ED: Regulation of aortic CuZn-superoxide dismutase with copper. Biochem J. 1987 Dec 15;248(3):663-8.


Despite non-measurable SOD activity in aorta, extracts from the 15-day-old-deficient-chick tissue contained as much, or slightly more, immunoreactive CuZn-SOD protein as age-matched control tissue.
1(0,0,0,1) Details
12175101 Harada S, Sugiyama E, Taki H, Shinoda K, Fujita T, Maruyama M, Kobayashi M: D-penicillamine cooperates with copper sulfate to enhance the surface expression of functional Fas antigen in rheumatoid synovial fibroblasts via the generation of hydrogen peroxide. Clin Exp Rheumatol. 2002 Jul-Aug;20(4):469-76.

0(0,0,0,0) Details