Name | GPCR |
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Synonyms | GPCR; Putative G protein coupled receptor |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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17425429 | Huang Y, Huang X, Zhang J, Gui J, Zhang Q: Subcellular localization and characterization of G protein-coupled receptor homolog from lymphocystis disease virus isolated in China. Viral Immunol. 2007 Spring;20(1):150-9. Quantitative analysis of apoptotic cells indicated that a considerable decrease in the apoptotic fraction of cells expressing GPCR, compared with the control cells, was detected after exposure to ActD and cycloheximide. |
15(0,0,1,10) | Details |
16914085 | Sanchez-Laorden BL, Sanchez-Mas J, Turpin MC, Garcia-Borron JC, Jimenez-Cervantes C: Variant amino acids in different domains of the human melanocortin 1 receptor impair cell surface expression. Cell Mol Biol (Noisy-le-grand). 2006 May 30;52(2):39-46. The alpha melanocyte-stimulating hormone receptor (MC1R) is a heptahelical G protein-coupled receptor (GPCR) found in the plasma membrane of melanocytes. |
1(0,0,0,1) | Details |
16739117 | Martin-Negrier ML, Charron G, Bloch B: Receptor recycling mediates plasma membrane recovery of D1 receptors in dendrites and axons after agonist-induced endocytosis in primary cultures of striatal neurons. Synapse. 2006 Sep 1;60(3):194-204. Recovery was unaffected by cycloheximide (70 microM) but was prevented by monensin (100 microM) that inhibits endosomal acidification and receptor recycling. These data suggest that dendritic and axonal D1Rs are internalized after agonist stimulation and targeted to the recycling pathway demonstrating that the machinery involved in GPCR endocytosis and recycling is functional both in dendrites and in axons. |
1(0,0,0,1) | Details |