Protein Information

Name IL 17
Synonyms CTLA 8; CTLA8; Cytotoxic T lymphocyte associated serine esterase 8; Cytotoxic T lymphocyte associated antigen 8; IL 17A; IL 17; IL17; IL17A…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
16951370 Rahman MS, Yamasaki A, Yang J, Shan L, Halayko AJ, Gounni AS: IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways. J Immunol. 2006 Sep 15;177(6):4064-71.

Moreover, IL-17A significantly induced eotaxin-1/CCL11 release and mRNA expression, an effect that was abrogated with cycloheximide and actinomycin D treatment.
14(0,0,1,9) Details
19204074 Ingram RJ, Isaacs JD, Kaur G, Lowther DE, Reynolds CJ, Boyton RJ, Collinge J, Jackson GS, Altmann DM: A role of cellular prion protein in programming T-cell cytokine responses in disease. FASEB J. 2009 Jun;23(6):1672-84. Epub 2009 Feb 9.


In experimental autoimmune encephalomyelitis, PrP-knockout mice showed enhanced disease in the face of reduced IL-17 responses.
1(0,0,0,1) Details