| Name | aquaporin 4 |
|---|---|
| Synonyms | AQP 4; AQP4; Aquaporin 4; HMIWC 2; HMIWC2; MIWC; Mercurial insensitive water channel; WCH 4… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18406487 | Morishima T, Aoyama M, Iida Y, Yamamoto N, Hirate H, Arima H, Fujita Y, Sasano H, Tsuda T, Katsuya H, Asai K, Sobue K: Lactic acid increases aquaporin 4 expression on the cell membrane of cultured rat astrocytes. Neurosci Res. 2008 May;61(1):18-26. Epub 2008 Jan 17. Under the conditions of de novo protein synthesis inhibition with cycloheximide, lactic acid increased the AQP4 expression level. |
87(1,1,1,7) | Details |
| 16895520 | Carmosino M, Procino G, Tamma G, Mannucci R, Svelto M, Valenti G: Trafficking and phosphorylation dynamics of AQP4 in -treated human gastric cells. Biol Cell. 2007 Jan;99(1):25-36. Using an endo-exocytosis assay we showed that, after washed out, internalized AQP4 recycled back to the cell surface, even in cells in which de novo protein synthesis was inhibited by cycloheximide. |
37(0,1,1,7) | Details |
| 16987239 | Ito H, Yamamoto N, Arima H, Hirate H, Morishima T, Umenishi F, Tada T, Asai K, Katsuya H, Sobue K: Interleukin-1beta induces the expression of aquaporin-4 through a nuclear factor-kappaB pathway in rat astrocytes. J Neurochem. 2006 Oct;99(1):107-18. It appeared that IL-1beta increased the level of AQP4 mRNA without involvement of de novo protein synthesis because cycloheximide, a protein synthesis inhibitor, did not inhibit the effects of IL-1beta. |
8(0,0,0,8) | Details |