Name | heparan sulfate proteoglycans |
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Synonyms | Fibroglycan; HSPG; HSPG 1; HSPG1; Heparan sulfate proteoglycan; Heparan sulfate proteoglycan 1 cell surface associated fibroglycan; Heparan sulfate proteoglycan core protein; SDC 2… |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16629467 | Yanagishita M, Tsuchida S, Yokoyama M, Inoue KA: [Effect of p-nitrophenyl-xyloside on the biosynthesis of proteoglycan in rat ovarian granulosa cells--analyses of glycosaminoglycan synthesis in the Golgi apparatus]. Kokubyo Gakkai Zasshi. 2006 Mar;73(1):20-5. Biosynthesis of heparan sulfate proteoglycans was reduced by approximately 50%, likely due to competition at the level of UDP-sugar precursors. [35S] incorporation was shut down by the addition of cycloheximide with an initial half time of approximately 2 hr in the presence of xyloside, while that in the absence of xyloside was about 20 min. |
31(0,1,1,1) | Details |
16807246 | Hayashida K, Johnston DR, Goldberger O, Park PW: Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway. J Biol Chem. 2006 Aug 25;281(34):24365-74. Epub 2006 Jun 28. Syndecans comprise a major family of cell surface heparan sulfate proteoglycans (HSPGs). Steady-state syndecan-1 mRNA was not increased by TGFbeta treatment and cycloheximide did not inhibit syndecan-1 induction by TGFbeta, indicating that TGFbeta induces syndecan-1 in a post-translational manner. |
1(0,0,0,1) | Details |