Protein Information

Name PAX3
Synonyms CDHS; HUP 2; HUP2; PAX 3; PAX3; PAX3/FKHR fusion gene; Paired box gene 3; Paired box homeotic gene 3…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
18335505 Mercado GE, Xia SJ, Zhang C, Ahn EH, Gustafson DM, Lae M, Ladanyi M, Barr FG: Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target. Genes Chromosomes Cancer. 2008 Jun;47(6):510-20.

The findings of cycloheximide inhibition and time-course studies are consistent with the hypothesis that the PAX3-FKHR protein acts directly on the MYCN gene at the transcriptional level.
38(0,1,1,8) Details