| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | oxydemeton-methyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18767757 | Ghadamyari M, Talebi K, Mizuno H, Kono Y: Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae). J Econ Entomol. 2008 Aug;101(4):1432-8. Susceptibility to oxydemeton-methyl and imidacloprid, and the inhibitory effects of oxydemeton-methyl and some organophosphate compounds on acetylcholinesterase (AChE) and carboxylesterase activity were studied in two populations (Karaj and Rasht) of green peach aphids, Myzus persicae (Sulzer). |
63(0,2,2,3) | Details |
| 8783813 | Worek F, Kirchner T, Backer M, Szinicz L: Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds. Arch Toxicol. 1996;70(8):497-503. For this purpose human erythrocyte AChE (EC 3.1.1.7) was inhibited (30 min) by chlorfenvinphos, dichlorvos, dicrotophos, heptenophos, mevinphos, monocrotophos, paraoxon, phosphamidon, trichlorfon, malaoxon, omethoate, oxydemeton-methyl or methamidophos by 85-98% of control. |
34(0,1,1,4) | Details |
| 15522601 | Anitha K, Mohan SV, Reddy SJ: Development of acetylcholinesterase sol-gel immobilized biosensor--an application towards oxydemeton methyl detection. Biosens Bioelectron. 2004 Nov 1;20(4):848-56. |
7(0,0,1,2) | Details |
| 11993279 | Pogacnik L, Franko M: Validation of different commercially available cholinesterases for pesticide toxicity test. Ann Chim. 2002 Jan-Feb;92(1-2):93-101. A systematic study of different commercially available cholinesterases (AChEs from electric eel, human erythrocytes, bovine erythrocytes and BuChE from horse serum) for the FIA determination of some frequently used organophosphate (paraoxon, oxydemeton-methyl, triazophos, diazionon) and (carbofuran, propoxur) pesticides was carried out. |
7(0,0,1,2) | Details |
| 19883634 | Eyer P, Worek F, Thiermann H, Eddleston M: Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning. Chem Biol Interact. 2009 Oct 31. It is generally accepted that inhibition of acetylcholinesterase (AChE) is the most important acute toxic action of organophosphorus compounds, leading to accumulation of followed by a dysfunction of cholinergic signaling. The former situation is seen in parathion, the latter in oxydemeton methyl poisoning. |
5(0,0,0,5) | Details |
| 19778163 | Eyer F, Worek F, Eyer P, Felgenhauer N, Haberkorn M, Zilker T, Thiermann H: Obidoxime in acute organophosphate poisoning: 1 - clinical effectiveness. Clin Toxicol. 2009 Sep;47(8):798-806. In this article we report clinical findings and activity of cholinesterase in plasma and acetylcholinesterase (AChE) in red blood cells. METHODS: We studied 34 atropinized patients with severe parathion, oxydemeton methyl, and dimethoate self-poisoning who were treated with obidoxime in a standard protocol. |
4(0,0,0,4) | Details |
| 10414801 | Thiermann H, Szinicz L, Eyer F, Worek F, Eyer P, Felgenhauer N, Zilker T: Modern strategies in therapy of organophosphate poisoning. Toxicol Lett. 1999 Jun 30;107(1-3):233-9. Using this protocol, six patients each with parathion or oxydemeton methyl poisoning were treated. At paraoxon concentrations > 0.1 microM obidoxime only partially reactivated acetylcholinesterase (AChE) of erythrocytes in vivo although reactivation could be assessed in vitro, which roughly fitted theoretical calculations. |
3(0,0,0,3) | Details |
| 10207609 | Worek F, Diepold C, Eyer P: Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics. Arch Toxicol. 1999 Feb;73(1):7-14. Human poisoning by organophosphates bearing two methoxy groups, e.g. by malathion, paraoxon-methyl, dimethoate and oxydemeton-methyl, is generally considered to be rather resistant to oxime therapy. The efficacy of obidoxime in reactivating dimethylphosphoryl-AChE was 40, 9 and 3 times higher than of HI 6, pralidoxime and HLo 7, respectively. |
3(0,0,0,3) | Details |
| 18968286 | Pogacnik L, Franko M: Optimisation of FIA system for detection of organophosphorus and pesticides based on cholinesterase inhibition. Talanta. 2001 May 30;54(4):631-41. The sensitivity of the bioanalytical FIA system containing different immobilised cholinesterases (AChEs from electric eel, human erythrocytes, bovine erythrocytes and BuChE from horse serum) for determination of organophosphorus and pesticides was tested. Responses to some frequently used organophosphorus (paraoxon, oxydemeton-methyl, triazophos) and (carbofuran, propoxur) pesticides were found to be dependent on the origin of cholinesterases. |
2(0,0,0,2) | Details |