| Name | gelatinases |
|---|---|
| Synonyms | 92 kDa gelatinase; Neutrophil collagenase; 92 kDa type IV collagenase; CLG4B; Collagenase type IV B; Collagenase type V; GEL B; GELB… |
| Name | oxytetracycline |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8410603 | Nip LH, Uitto VJ, Golub LM: Inhibition of epithelial cell matrix metalloproteinases by tetracyclines. J Periodontal Res. 1993 Sep;28(5):379-85. Furthermore, epithelial cells cultured with doxycycline, oxytetracycline and de-dimethylaminotetracycline in concentrations ranging from 1 to 50 micrograms/ml showed a marked reduction in secreted gelatinase activity when grown in alpha minimum essential medium in the absence of fetal calf serum. |
82(1,1,1,2) | Details |
| 1847418 | Gabler WL, Creamer HR: Suppression of human neutrophil functions by tetracyclines. J Periodontal Res. 1991 Jan;26(1):52-8. Evidence has suggested that this inhibition results from the ability of this family of antimicrobial drugs to bind divalent cations such as Ca2+ and Zn2+, two cations that are required for full expression of activity of metalloproteinases such as collagenase and gelatinase. |
1(0,0,0,1) | Details |