Protein Information

Name phosphoenolpyruvate carboxykinase
Synonyms PCK 1; PCK1; PEP carboxykinase; PEPCK cytosolic; PEPCK 1; PEPCK C; PEPCKC…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
17213664 Kimura K, Tawara S, Igarashi K, Takenaka A: Effect of various radical generators on insulin-dependent regulation of hepatic gene expression. Biosci Biotechnol Biochem. 2007 Jan;71(1):16-22. Epub 2007 Jan 7.

Paraquat (PQ) and H2O2 inhibited insulin-dependent repression of insulin-like growth factor-binding protein-1 (IGFBP-1) and phosphoenolpyruvate carboxykinase (PEPCK) gene expression.
81(1,1,1,1) Details
16555045 Tomita M, Okuyama T, Katsuyama H, Ishikawa T: Paraquat-induced gene expression in rat kidney. . Arch Toxicol. 2006 Oct;80(10):687-93. Epub 2006 Mar 23.

Expression of six genes had increased significantly by 3 h after the first injection: metallothionein-1 (MT-1), phosphoenolpyruvate carboxykinase, Na/K-transporting ATPase beta1 subunit, glutamate oxaloacetic transaminase, glutathione-S-transferase, and heme oxygenase-1 (HO-1).
1(0,0,0,1) Details