Protein Information

Name insulin like growth factor I
Synonyms IBP1; MGF; IBP1; IGF 1; IGF IA; IGF IB; IGF1; IGFI…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
17979500 Li Q, Yang X, Sreejayan N, Ren J: Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat-induced cardiomyocyte dysfunction: role of oxidative stress. Rejuvenation Res. 2007 Dec;10(4):501-12.
81(1,1,1,1) Details
15761239 Holzenberger M: The role of insulin-like signalling in the regulation of ageing. Horm Res. 2004;62 Suppl 1:89-92.


Inactivation of insulin-like growth factor I (IGF-I) signalling pathways have been shown to extend lifespans in various lower species, including the nematode Caenorhabditis elegans.
1(0,0,0,1) Details