| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17364237 | Ahmed M, Rocha JB, Mazzanti CM, Morsch AL, Cargnelutti D, Correa M, Loro V, Morsch VM, Schetinger MR: Malathion, carbofuran and paraquat inhibit Bungarus sindanus (krait) venom acetylcholinesterase and human serum butyrylcholinesterase in vitro. Ecotoxicology. 2007 May;16(4):363-9. Epub 2007 Mar 16. |
119(1,2,3,4) | Details |
| 17024560 | Wijeyaratne WM, Pathiratne A: Acetylcholinesterase inhibition and gill lesions in Rasbora caverii, an indigenous fish inhabiting rice field associated waterbodies in Sri Lanka. Ecotoxicology. 2006 Oct;15(7):609-19. Epub 2006 Oct 6. Laboratory studies showed that prior exposure of R. caverii to Paraquat (2 microg l (-1), 7 days) enhanced the extent of inhibition of brain AChE activity induced by Fenthion (3 microg l (-1)) or a mixture of Fenthion (3 microg l (-1)) and Phenthoate (5 microg l (-1)). |
85(1,1,1,5) | Details |
| 17654339 | Alcaro S, Arcone R, Vecchio I, Ortuso F, Gallelli A, Pasceri R, Procopio A, Iannone M: Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds. SAR QSAR Environ Res. 2007 Jul-Sep;18(5-6):595-602. |
83(1,1,1,3) | Details |
| 11281253 | El-Demerdash FM, Yousef MI, Elagamy EI: Influence of paraquat, and cadmium on the activity of some serum enzymes and protein electrophoretic behavior (in vitro). J Environ Sci Health B. 2001 Jan;36(1):29-42. In vitro study for the determination of the toxicity of some pesticides (glyphospate and paraquat) and cadmium (CdCl2) on the activities of serum acetylcholinesterase (AChE), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AlP), and acid phosphatase (AcP) is described. |
8(0,0,1,3) | Details |
| 10740894 | Hathway DE: Toxic action/toxicity. Biol Rev Camb Philos Soc. 2000 Feb;75(1):95-127. Covalent chemical reactions with second-order (SN2) kinetics characterize Hg and Cd poisonings, the reactions of organophosphates and phosphonates with acetylcholinesterase and neurotoxic esterase and the reaction sequence whereby Paraquat accepts electrons and generates under aerobic conditions. |
7(0,0,1,2) | Details |
| 15922524 | Hernandez AF, Lopez O, Rodrigo L, Gil F, Pena G, Serrano JL, Parron T, Alvarez JC, Lorente JA, Pla A: Changes in erythrocyte enzymes in humans long-term exposed to pesticides: influence of several markers of individual susceptibility. Toxicol Lett. 2005 Oct 15;159(1):13-21. Changes in erythrocyte delta-aminolevulinic acid dehydratase (ALA-D) have been reported after exposure to different pesticides, including organophosphates and paraquat. Acetylcholinesterase (AChE) was used as a reference biomarker. |
4(0,0,0,4) | Details |
| 18085124 | Goel A, Aggarwal P: Pesticide poisoning. Natl Med J India. 2007 Jul-Aug;20(4):182-91. Ingestion of paraquat causes severe inflammation of the throat, corrosive injury to the gastrointestinal tract, renal tubular necrosis, hepatic necrosis and pulmonary fibrosis. Organophosphate compounds inhibit acetylcholinesterase resulting in acute toxicity. |
1(0,0,0,1) | Details |
| 10794404 | Satoh T, Hosokawa M: Organophosphates and their impact on the global environment. Neurotoxicology. 2000 Feb-Apr;21(1-2):223-7. The results of the forensic studies showed that methylphosphonic acid, the hydrolysis product of sarin, bound to AChE in the cerebellums of the victims was separated and identified using GCMS. (3) A sensitive and rapid biomarker of OP-poisoning. This seems to be influenced by the decrease of the incidences of paraquat having extremely high toxicity. |
1(0,0,0,1) | Details |