Protein Information

Name SP A
Synonyms 35 kDa pulmonary surfactant associated protein; PSAP; Alveolar proteinosis protein; PSP A; PSPA; SFTP 1; SFTP1; SFTPA…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
17174135 Hantson P, Weynand B, Doyle I, Bernand A, Hermans C: Pneumoproteins as markers of paraquat lung injury: a clinical case. J Forensic Leg Med. 2008 Jan;15(1):48-52. Epub 2006 Dec 14.

The immunostaining study showed that the labeling for SP-A and SP-B was reduced or absent following paraquat toxicity, while Clara cells were relatively preserved.
85(1,1,1,5) Details
17616020 Gil HW, Oh MH, Woo KM, Lee EY, Oh MH, Hong SY: Relationship between pulmonary surfactant protein and lipid peroxidation in lung injury due to paraquat intoxication in rats. Korean J Intern Med. 2007 Jun;22(2):67-72.
23(0,0,3,8) Details
14630065 Ridd K, Alexander DJ, Reed CJ: Foetal rat lung epithelial (FRLE) cells: partial characterisation and response to pneumotoxins. Toxicol In Vitro. 2004 Feb;18(1):79-88.


The cells were found to have retained some of the features of their progenitor cells, namely the expression of cytokeratin proteins, specifically cytokeratin 18, and the ability to actively accumulate the non-selective contact herbicide paraquat.
0(0,0,0,0) Details