| Name | quinone reductase |
|---|---|
| Synonyms | Quinone oxidoreductase; Crystallin zeta; Zeta crystallin; Crystallin zetas; Quinone oxidoreductases; Zeta crystallins; CRYZ; Zeta crystalline… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10425747 | Hirai K, Pan J, Shimada H, Izuhara T, Kurihara T, Moriguchi K: Cytochemical energy-filtering transmission electron microscopy of mitochondrial free radical formation in paraquat cytotoxicity. J Electron Microsc. 1999;48(3):289-96. When isolated intact mitochondria from rat livers were incubated in a medium containing paraquat and a mitochondrial -quinone oxidoreductase activity generated anions to cause the destruction of mitochondria which resulted in cell death. |
32(0,1,1,2) | Details |
| 17923370 | Hong Y, Wang G, Maier RJ: The quinone reductase MdaB confers oxidative stress resistance to Helicobacter hepaticus. Microb Pathog. 2008 Feb;44(2):169-74. Epub 2007 Sep 6. The mdaB mutant was also more sensitive to oxidative stress reagents such as H (2) O (2), cumene hydroperoxide, t-butyl hydroperoxide, and paraquat. |
2(0,0,0,2) | Details |
| 17409708 | Ohashi T, Satoh T, Kuwata M, Fujimura T, Taketani S: [Visualization and evaluation of the promoter activities of genes for stress-inducible proteins in response to environmental pollutants]. Yakugaku Zasshi. 2007 Apr;127(4):757-64. We examined the systematic assay of the reporter gene for the assessment of heavy metals and organic chemical pollutants using the reporter plasmids carrying stress-responsive elements fused to the green fluorescence protein (GFP) gene as follows: metallothionein (MTIIA), heme oxigenase-1 (HO-1), quinone reductase (ARE), and c-fos genes. The treatment of COS7 cells in which the c-fos gene promoter-, ARE-, or HO-1 enhancer-fused GFP with a low concentration of NaAsO (2) was introduced led to the detection of the fluorescent cells, and an agrichemical paraquat enhanced the fluorescence of ARE or HO-1 enhancer-transfected cells. |
1(0,0,0,1) | Details |
| 15576767 | Loo CY, Mitrakul K, Jaafar S, Gyurko C, Hughes CV, Ganeshkumar N: Role of a nosX homolog in Streptococcus gordonii in aerobic growth and biofilm formation. J Bacteriol. 2004 Dec;186(24):8193-206. Located downstream are two genes, qor1 and qor2, predicted to encode two putative quinone oxidoreductases. Expression of nosX, measured by the beta-galactosidase activity of the nosX::Tn917-lac mutant, was growth-phase dependent and enhanced when grown under aerobic conditions or in the presence of paraquat. |
1(0,0,0,1) | Details |
| 17320357 | Park JS, Li YF, Bai Y: Yeast NDI1 improves oxidative phosphorylation capacity and increases protection against oxidative stress and cell death in cells carrying a Leber's hereditary optic neuropathy mutation. Biochim Biophys Acta. 2007 May;1772(5):533-42. Epub 2007 Jan 26. The NDI1 gene, which encodes the internal -quinone oxidoreductase in Saccharomyces cerevisiae, was introduced into the nuclear genome of a mitochondrial defective human cell line, Le1.3.1, carrying the G11778A mutation. Finally, transformants were also shown to be desensitized to induction to apoptosis and also exhibit greater resistance to paraquat-induced cell death. |
1(0,0,0,1) | Details |
| 10699569 | Ali S, Diwakar G, Pawa S: Paraquat induces different pulmonary biochemical responses in Wistar rats and Swiss mice. Chem Biol Interact. 2000 Mar 1;125(2):79-91. As a protective response, -specific quinone reductase is induced in rats, while catalase is induced in mice. |
1(0,0,0,1) | Details |
| 14977943 | Wang G, Maier RJ: An quinone reductase of Helicobacter pylori plays an important role in oxidative stress resistance and host colonization. Infect Immun. 2004 Mar;72(3):1391-6. The mdaB mutant is also more sensitive to H (2) O (2), organic hydroperoxides, and the -generating agent paraquat. |
2(0,0,0,2) | Details |