| Name | PK1 |
|---|---|
| Synonyms | Black mamba toxin related protein; PRK 1; PRK1; EG VEGF; EGVEGF; Endocrine gland derived vascular endothelial growth factor; Mambakine; PK1… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11039594 | Kiyomiya K, Matsushita N, Matsuo S, Kurebe M: Roles of radical production and lipid peroxidation in the cytotoxicity of cephaloridine on cultured renal epithelial cells (LLC-PK1). J Vet Med Sci. 2000 Sep;62(9):977-81. The levels of -dependent peroxide and production by microsomes prepared from LLC-PK1 cells, and by -cytochrome P-450 reductase purified from the rat renal cortex were significantly increased by paraquat. |
33(0,1,1,3) | Details |
| 12537968 | Li W, Choy DF, Lam MS, Morgan T, Sullivan ME, Post JM: Use of cultured cells of kidney origin to assess specific cytotoxic effects of nephrotoxins. Toxicol In Vitro. 2003 Feb;17(1):107-13. The cell types were the porcine normal kidney tubular epithelial cell line (LLC-PK1), the primary human renal proximal tubular epithelial cells (hRPTEC) and the human liver cell line (HepG2). Four known nephrotoxins, cisplatin, cyclosporin A and paraquat, were tested in this cell-based assay to evaluate cytotoxicity on drug exposure. |
2(0,0,0,2) | Details |
| 11327515 | Machaalani R, Lazzaro V, Duggin GG: The characterisation and uptake of paraquat in cultured baboon kidney proximal tubule cells (bPTC). Hum Exp Toxicol. 2001 Feb;20(2):90-9. The cytotoxic threshold for PQ in these cells was determined and compared to the LLC-PK1 and MDCK cells. |
2(0,0,0,2) | Details |