| Name | succinate dehydrogenase cytochrome b |
|---|---|
| Synonyms | CYB560; CYBL; Cytochrome B large subunit of complex II; Integral membrane protein C2 3; Integral membrane protein CII 3; Integral membrane protein CII 3b; PGL 3; PGL3… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17636259 | Szeto SS, Reinke SN, Sykes BD, Lemire BD: -binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate and lead to the accumulation of J Biol Chem. 2007 Sep 14;282(37):27518-26. Epub 2007 Jul 18. The SDH3 R47K, SDH4 D88E, and SDH4 D88N mutants are sensitive to hyperoxia and paraquat and have elevated rates of production in vitro and in vivo. |
32(0,1,1,2) | Details |
| 11237107 | Ishii N: Oxidative stress and aging in Caenorhabditis elegans. Free Radic Res. 2000 Dec;33(6):857-64. A mev-1 (kn1) mutant of Caenorhabditis elegans, isolated on the basis of its methyl viologen (paraquat) hypersensitivity, is also hypersensitive to elevated levels. We have cloned mev-1 gene by transformation rescue and found that it is, in fact, the previously sequenced gene (cyt-1) that encodes succinate dehydrogenase cytochrome b. |
1(0,0,0,1) | Details |
| 13129931 | Guo J, Lemire BD: The -binding site of the Saccharomyces cerevisiae - oxidoreductase is a source of J Biol Chem. 2003 Nov 28;278(48):47629-35. Epub 2003 Sep 16. The mev-1 mutation in the Caenorhabditis elegans gene encoding the homolog of the SDHC subunit results in premature aging and hypersensitivity to oxidative stress. The P190Q and S94E mutants have reduced - oxidoreductase activities and are hypersensitive to and paraquat. |
1(0,0,0,1) | Details |
| 19233206 | Huang J, Lemire BD: Mutations in the C. elegans succinate dehydrogenase iron- subunit promote generation and premature aging. J Mol Biol. 2009 Apr 3;387(3):559-69. Epub 2009 Feb 20. Mutations in the human SDHB, SDHC and SDHD genes are responsible for the development of paraganglioma and pheochromocytoma, tumors of the head and neck or the adrenal medulla, respectively. |
1(0,0,0,1) | Details |