| Name | catalase |
|---|---|
| Synonyms | CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19027846 | Peng J, Stevenson FF, Oo ML, Andersen JK: -enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation. Free Radic Biol Med. 2009 Jan 15;46(2):312-20. Epub 2008 Nov 7. Furthermore, pretreatment with the synthetic superoxide dismutase/catalase mimetic, EUK-189, significantly decreased microglial activation mediated by combined paraquat and iron treatment. |
81(1,1,1,1) | Details |
| 17596439 | Peng J, Peng L, Stevenson FF, Doctrow SR, Andersen JK: and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration. J Neurosci. 2007 Jun 27;27(26):6914-22. Furthermore, pretreatment with the synthetic superoxide dismutase/catalase mimetic, EUK-189, significantly attenuated neuronal death mediated by combined paraquat and iron treatment. |
81(1,1,1,1) | Details |
| 16828145 | Wiegand C, Pehkonen S, Akkanen J, Penttinen OP, Kukkonen JV: Bioaccumulation of paraquat by Lumbriculus variegatus in the presence of dissolved natural organic matter and impact on energy costs, biotransformation and antioxidative enzymes. Chemosphere. 2007 Jan;66(3):558-66. Epub 2006 Jul 7. Bioavailability of paraquat to L. variegates as well as activities of antioxidative enzymes catalase (CAT) and peroxidase (POD) and biotransformation enzyme soluble glutathione S-transferase (sGST) were assessed without and in the presence of DNOM. |
6(0,0,1,1) | Details |
| 11200086 | Bellaire BA, Carmody J, Braud J, Gossett DR, Banks SW, Lucas MC, Fowler TE: Involvement of abscisic acid-dependent and -independent pathways in the upregulation of antioxidant enzyme activity during NaCl stress in cotton callus tissue. Free Radic Res. 2000 Nov;33(5):531-45. Treatment with NaCl resulted in a rapid increase (within 30 minutes) in the ABA levels of the callus tissue, and the NaCl, ABA, and paraquat treatments induced rapid increases in the activities of superoxide dismutase, catalase, peroxidase, and glutathione reductase. |
6(0,0,1,1) | Details |
| 10195331 | Li X, Sun AY: Paraquat induced activation of transcription factor AP-1 and apoptosis in PC12 cells. J Neural Transm. 1999;106(1):1-21. Moreover, cells were also protected from paraquat toxicity in the presence of antioxidant defense enzymes SOD and catalase. |
6(0,0,1,1) | Details |
| 19324099 | Pungartnik C, Melo SC, Basso TS, Macena WG, Cascardo JC, Brendel M: Reactive species and autophagy play a role in survival and differentiation of the phytopathogen Moniliophthora perniciosa. Fungal Genet Biol. 2009 Jun-Jul;46(6-7):461-72. Epub 2009 Mar 24. During different stages preceding basidiocarp formation MpATG8 and the two catalase-encoding genes MpCTA1 and MpCTT1 were expressed continuously. Mono-/dikaryotic or -grown cells and basidiospores were exposed to the oxidative stress-inducing mutagens H (2) O (2) and Paraquat as well as to pre-dominantly DNA damaging 4-nitroquinoline-1-oxide and UVC irradiation. |
1(0,0,0,1) | Details |
| 12470895 | Yanase S, Yasuda K, Ishii N: Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span. Mech Ageing Dev. 2002 Nov;123(12):1579-87. We found that daily short-term exposure (3 h) to hyperoxia further extended the life span of age-1, a phenomenon known as an adaptive response. age-1 also showed resistance to paraquat and heat. We measured mRNA levels of superoxide dismutase genes (sod-1 through 4), catalase genes (clt-1 and ctl-2), known to encode anti-oxidant enzymes, and found they were elevated in age-1 young adults. |
1(0,0,0,1) | Details |
| 16986793 | Pflugmacher S, Jung K, Lundvall L, Neumann S, Peuthert A: Effects of cyanobacterial toxins and cyanobacterial cell-free crude extract on germination of alfalfa (Medicago sativa) and induction of oxidative stress. Environ Toxicol Chem. 2006 Sep;25(9):2381-7. These systems consist of enzymes, such as superoxide dismutase, catalase, and peroxidase, and nonenzymatic substances, such as or vitamins. |
1(0,0,0,1) | Details |
| 19778406 | Ding HD, Zhang XH, Xu SC, Sun LL, Jiang MY, Zhang AY, Jin YG: Induction of protection against paraquat-induced oxidative damage by abscisic acid in maize leaves is mediated through mitogen-activated protein kinase. J Integr Plant Biol. 2009 Oct;51(10):961-72. Two inhibitors also suppressed the total activities of the antioxidant enzymes superoxide dismutase (SOD, EC 1.15.1.1), catalase (CAT, EC 1.11.1.6), peroxidase (APX, EC 1.11.1.11), and glutathione reductase (GR, EC 1.6.4.2). |
1(0,0,0,1) | Details |
| 19583935 | Cao XG, Hou LL, Chen JX, Lu Q: Effects of Bushen Kangshuai Tang in retrieving oxidative stress-induced reproductive defects in Caenorhabditis elegans. Zhong Xi Yi Jie He Xue Bao. 2009 Jun;7(6):532-40. RESULTS: Ultraviolet irradiation, heat-shock, and paraquat treatment could significantly reduce egg number in uterus and brood size, increase generation time, and suppress activities of catalase and superoxide dismutase of the treated wild-type N2 nematodes. |
81(1,1,1,1) | Details |
| 10480324 | Komada F, Nishiguchi K, Tanigawara Y, Iwakawa S, Okumura K: Effects of secretable SOD delivered by genetically modified cells on /xanthine oxidase and paraquat-induced cytotoxicity in vitro. Biol Pharm Bull. 1999 Aug;22(8):846-53. Following addition of catalase, the sensitivity of these genetically modified cells to paraquat became equivalent to that of host cells. |
81(1,1,1,1) | Details |
| 17569284 | Ray S, Sengupta A, Ray A: Effects of paraquat on anti-oxidant system in rats. Indian J Exp Biol. 2007 May;45(5):432-8. Glutathione reductase and glucose-6-phosphate dehydrogenase activity decreased, whereas the activity of glutathione-S-transferase, peroxidase, catalase and superoxide dismutase increased in paraquat exposure. |
6(0,0,1,1) | Details |
| 16394531 | Tieppo M, Porawski M, Salvador M, Moreira AJ, Collado PS, Gonzalez-Gallego J, Marroni NP: Croton cajucara Benth. leaf extract scavenges the stable free radical DPPH and protects against oxidative stress induced by paraquat. Biol Pharm Bull. 2006 Jan;29(1):161-5. Croton cajucara extract increased GPx and catalase activities in paraquat treated-animals by 342% and 70%, respectively. |
6(0,0,1,1) | Details |
| 10752666 | Tsukamoto M, Tampo Y, Sawada M, Yonaha M: Paraquat-induced membrane dysfunction in pulmonary microvascular endothelial cells. J Korean Med Sci. 2003 Oct;18(5):649-54. Lactate dehydrogenase release 72 hr after exposure to 0.5 mM paraquat was prevented strongly by catalase (1000 units/ml), but weakly by superoxide dismutase (1000 units/ml). |
6(0,0,1,1) | Details |
| 10598954 | Yang MK, Kim YG: Protective role of -132 against paraquat-induced oxidative stress in the livers of senescence-accelerated mice. J Toxicol Environ Health A. 1999 Nov 12;58(5):289-97. In addition, Ge-132 significantly elevated the activities of hepatic superoxide dismutase (SOD) and catalase following PQ pretreatment. |
1(0,0,0,1) | Details |
| 12715897 | Missirlis F, Rahlfs S, Dimopoulos N, Bauer H, Becker K, Hilliker A, Phillips JP, Jackle H: A putative peroxidase of Drosophila encodes a thioredoxin peroxidase that provides resistance against oxidative stress but fails to complement a lack of catalase activity. Biol Chem. 2003 Mar;384(3):463-72. The results suggest that GTPx-1 is part of the Drosophila Trx antioxidant defense system but acts in a genetically distinct pathway or in a different cellular compartment than catalase. |
1(0,0,0,1) | Details |
| 12722655 | Vorob'eva LI, Khodzhaev EIu, Ponomareva GM, Briukhanov AL: [Extracellular protein metabolite of Luteococcus japonicus subsp. casei reactivates cells subjected to oxidative stress]. Prikl Biokhim Mikrobiol. 2003 Mar-Apr;39(2):202-7. A protein exometabolite isolated from the culture liquid of Luteococcus japonicus subsp. casei reactivates the cells of this microorganism, following H2O2 or paraquat-induced oxidative stress. The resistance of L. casei cells to these oxidizers is accounted for by the high activity of superoxide dismutase and catalase. |
1(0,0,0,1) | Details |
| 10805594 | Miyagawa Y, Tamoi M, Shigeoka S: Evaluation of the defense system in chloroplasts to photooxidative stress caused by paraquat using transgenic tobacco plants expressing catalase from Escherichia coli. Plant Cell Physiol. 2000 Mar;41(3):311-20. We evaluated the defense system in chloroplasts to photooxidative stress imposed by paraquat treatment under illumination in transgenic tobacco plants with increased tolerance to drought stress at a high light intensity produced by catalase from Escherichia coli targeted to chloroplasts [Shikanai et al. (1998) FEBS Lett. 428: 47]. |
37(0,1,2,2) | Details |
| 15946937 | Peng J, Stevenson FF, Doctrow SR, Andersen JK: Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. J Biol Chem. 2005 Aug 12;280(32):29194-8. Epub 2005 Jun 9. |
37(0,1,2,2) | Details |
| 16923890 | LeBlanc JJ, Davidson RJ, Hoffman PS: Compensatory functions of two alkyl hydroperoxide reductases in the oxidative defense system of Legionella pneumophila. J Bacteriol. 2006 Sep;188(17):6235-44. To establish a catalatic function for these two systems, we expressed L. pneumophila ahpC1 or ahpC2 in a catalase/peroxidase mutant of Escherichia coli and demonstrated restoration of H2O2 resistance by a disk diffusion assay. ahpC1::Km and ahpC2D::Km chromosomal deletion mutants were two- to eightfold more sensitive to H2O2, tert-butyl hydroperoxide, cumene hydroperoxide, and paraquat than the wild-type L. pneumophila, a phenotype that could be restored by trans-complementation. |
32(0,1,1,2) | Details |
| 15159446 | Osakada F, Kawato Y, Kume T, Katsuki H, Sugimoto H, Akaike A: Serofendic acid, a -containing diterpenoid derived from fetal calf serum, attenuates reactive species-induced oxidative stress in cultured striatal neurons. J Pharmacol Exp Ther. 2004 Oct;311(1):51-9. Epub 2004 May 24. Paraquat caused neuronal death, which was inhibited by a cell-permeable superoxide dismutase (SOD) mimetic, Mn (III) tetrakis (4- (Mn-TBAP); a cell-permeable SOD/catalase mimetic, EUK-134 3-methoxy N,N'-bis (salicylidene) ethylenediamine and a ferrous ion chelator, 2,2'-dipyridyl, in rat striatal cultures. |
31(0,1,1,1) | Details |
| 15093102 | Patra J, Panda BB: A comparison of biochemical responses to oxidative and metal stress in seedlings of barley, Hordeum vulgare L. Environ Pollut. 1998;101(1):99-105. Biochemical responses on the bases of activities of antioxidant enzymes; peroxidase, catalase, superoxide dismutase and glutathione reductase as well as estimations of total protein, lipid peroxidation and thiols in the form of protein, non-protein, and phytochelatin measured in growing seedlings of barley, Hordeum vulgare L., from Day 2 through 8 were compared following treatment of seeds for 2 h with oxidative agents, paraquat 5 x 10 (-5), 10 (-4), 10 (-3) M, H2O2 10 (-3), 5 x 10 (-3), 10 (-2) M and a metal salt, CdSO4 10 (-5), 10 (-4), 10 (-3) M. |
6(0,0,1,1) | Details |
| 19938450 | Zhao Y, Li J, Chen Y, Huang H, Yu Z: [Impact of exogenous paraquat on enzyme exudation and biochemical changes of lignin degradation fungi]. J Exp Bot. 2002 Dec;53(379):2401-10. Also, addition of paraquat enhanced activity of superoxide dismutase (SOD) and catalase (CAT) in the first 48 h. |
6(0,0,1,1) | Details |
| 12160934 | Michan S, Lledias F, Baldwin JD, Natvig DO, Hansberg W: Regulation and oxidation of two large monofunctional catalases. . Free Radic Biol Med. 2002 Aug 15;33(4):521-32. It was induced under stress conditions, such as H (2) O (2), paraquat, cadmium, heat shock, and treatment. |
5(0,0,0,5) | Details |
| 17644593 | Guina T, Radulovic D, Bahrami AJ, Bolton DL, Rohmer L, Jones-Isaac KA, Chen J, Gallagher LA, Gallis B, Ryu S, Taylor GK, Brittnacher MJ, Manoil C, Goodlett DR: MglA regulates Francisella tularensis subsp. novicida (Francisella novicida) response to starvation and oxidative stress. J Bacteriol. 2007 Sep;189(18):6580-6. Epub 2007 Jul 20. The F. novicida mglA mutant exhibited decreased survival during stationary-phase growth and increased susceptibility to killing by generated by the redox-cycling agent paraquat. The F. novicida mglA mutant also showed increased survival upon exposure to peroxide, likely due to increased amounts of the catalase KatG. |
1(0,0,0,1) | Details |
| 15754033 | Tomita M, Katsuyama H, Okuyama T, Hidaka K, Minatogawa Y: Changes in gene expression level for defense system enzymes against oxidative stress and level in rat administered paraquat. Int J Mol Med. 2005 Apr;15(4):689-93. At 16 h after PQ intake, the mRNA expression level of glutathione reductase (GR) showed the greatest increase, and those of catalase (CAT) and manganese-superoxide dismutase (MnSOD) showed more modest increases. |
1(0,0,0,1) | Details |
| 10569645 | Franco AA, Odom RS, Rando TA: Regulation of antioxidant enzyme gene expression in response to oxidative stress and during differentiation of mouse skeletal muscle. Free Radic Biol Med. 1999 Nov;27(9-10):1122-32. To investigate this important homeostatic response, we studied the effect of oxidative challenges on the expression of genes encoding the antioxidant enzymes Cu,Zn-superoxide dismutase (CuZnSOD), Mn-superoxide dismutase (MnSOD), peroxidase (GPx), and catalase (CAT) in myotube cultures. Using Northern blot analysis, we found that treatment with the pro-oxidant paraquat resulted in time- and dose-dependent increases of transcript levels that were greatest for GPx and CAT (approximately 4-5 fold). |
1(0,0,0,1) | Details |
| 19508366 | Wan X, Tan J, Lu S, Lin C, Hu Y, Guo Z: Increased tolerance to oxidative stress in transgenic tobacco expressing a wheat oxidase gene via induction of antioxidant enzymes is mediated by H2O2. Physiol Plant. 2009 May;136(1):30-44. Epub 2009 Feb 12. Higher activities and transcripts of antioxidant enzymes (superoxide dismutase, catalase, peroxidase and glutathione reductase) were observed in the transgenic plants compared to their wild-type controls under normal growth conditions. |
1(0,0,0,1) | Details |
| 10380622 | Kimura Y, Araki Y, Takenaka A, Igarashi K: Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. Biosci Biotechnol Biochem. 1999 May;63(5):799-804. In addition, catalase activity in the liver mitochondrial fraction was markedly decreased by feeding the paraquat diet, this decrease being partially suppressed by supplementing the paraquat diet with nasunin. |
31(0,1,1,1) | Details |
| 10993144 | Igarashi K, Kimura Y, Takenaka A: Preventive effects of dietary cabbage acylated anthocyanins on paraquat-induced oxidative stress in rats. Biosci Biotechnol Biochem. 2000 Aug;64(8):1600-7. In addition, the catalase activity in the liver mitochondrial fraction was markedly decreased by feeding on the paraquat diet, this decrease being partially suppressed by supplementing the paraquat diet with acylated anthocyanins. |
31(0,1,1,1) | Details |
| 18284659 | Choi NH, Kim JG, Yang DJ, Kim YS, Yoo MA: Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor. Aging Cell. 2008 Jun;7(3):318-34. Epub 2008 Feb 13. We determined that oxidative stress, induced by paraquat treatment or loss of catalase function, mimicked the changes associated with aging in the midgut. |
31(0,1,1,1) | Details |
| 12384824 | Hauck SJ, Aaron JM, Wright C, Kopchick JJ, Bartke A: Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm Metab Res. 2002 Sep;34(9):481-6. We measured activities of antioxidant enzymes Cu/Zn superoxide dismutase (SOD), catalase (CAT), and peroxidase (GPx) and quantified free-radical damage by lipid peroxidation (LP) and protein oxidation (PO) measurements in liver and kidney tissues, and evaluated the response to paraquat-induced oxygen toxicity in the long-living GH receptor/binding protein gene knockout (GHR-KO) mouse. |
31(0,1,1,1) | Details |
| 14759608 | Chen X, Liang H, Van Remmen H, Vijg J, Richardson A: Catalase transgenic mice: characterization and sensitivity to oxidative stress. PLoS One. 2009 Nov 24;4(11):e8011. Hepatocytes and fibroblasts from the Tg (CAT)(+/+) mice were more resistant to peroxide-induced cell death but were more sensitive to paraquat and TNFalpha toxicity. |
4(0,0,0,4) | Details |
| 16341707 | Schmidt M, Grief J, Feierabend J: Mode of translational activation of the catalase (cat1) mRNA of rye leaves (Secale cereale L.) and its control through blue light and reactive Planta. 2006 Mar;223(4):835-46. Epub 2006 Feb 23. Peroxides (H (2) O (2), tertiary butyl hydroperoxide) and conditions enforcing an H (2) O (2) accumulation in the leaves (aminotriazole, paraquat) also caused an activation of the cat1 mRNA. |
4(0,0,0,4) | Details |
| 10629192 | Gibson CM, Mallett TC, Claiborne A, Caparon MG: Contribution of oxidase to aerobic metabolism of Streptococcus pyogenes. J Bacteriol. 2000 Jan;182(2):448-55. However, the mutants were unable to grow under high-O (2) conditions and demonstrated enhanced sensitivity to the -generating agent paraquat. Either the addition of catalase to the culture medium of the mutants or the introduction of a heterologous peroxidase into the mutants eliminated the accumulation of H (2) O (2) and rescued the growth defect of the mutants under high-O (2) conditions in carbohydrate-limited liquid medium. |
1(0,0,0,1) | Details |
| 10498818 | Noack H, Possel H, Rethfeldt C, Keilhoff G, Wolf G: mediated damage and lowered tolerance in primary cortical glial cultures after induction of the inducible isoform of NOS. Glia. 1999 Oct;28(1):13-24. Among the ROS scavenging enzymes superoxide dismutase (Cu/Zn- and Mn-isoform), peroxidase and catalase only mitochondrial Mn-SOD was found to be upregulated in the course of i-NOS induction (Western blots). Elevated levels of generated either intracellularly by paraquat or extracellularly via xanthine oxidase and resulted dose-dependently in a larger decline of cell viability in the .NO forming cultures compared to controls (release of lactate dehydrogenase, citrate synthase, stainability by propidium iodide, and tetramethylrhodamine). |
1(0,0,0,1) | Details |
| 18588894 | Cai GB, Bae YA, Kim SH, Sohn WM, Lee YS, Jiang MS, Kim TS, Kong Y: Vitellocyte-specific expression of phospholipid hydroperoxide peroxidases in Clonorchis sinensis. Int J Parasitol. 2008 Dec;38(14):1613-23. Epub 2008 Jun 7. Our data may suggest a concerted or a specialised function between a thioredoxin-dependent enzyme (s) and GPx in protecting against H (2) O (2)-derived damage during maturation of the embryo and formation of the eggshell, in these catalase-lacking trematode parasites. Oxidative stimulation of viable worms with H (2) O (2) or paraquat resulted in 1.5- to 2-fold induction of the GPx activity. |
1(0,0,0,1) | Details |
| 10490287 | Lagrange P, Romero IA, Minn A, Revest PA: Transendothelial permeability changes induced by free radicals in an in vitro model of the blood-brain barrier. Free Radic Biol Med. 1999 Sep;27(5-6):667-72. We have recently shown that a range of xenobiotics, including nitrofurazone, and methylviologen (paraquat) may undergo monoelectronic redox cycling in isolated brain capillaries, giving rise to reactive species. Pre-incubation with superoxide dismutase and catalase blocked changes in permeability to control levels in a dose-dependent manner, suggesting the involvement of reactive species in -induced BBB opening. |
1(0,0,0,1) | Details |
| 19329562 | Oracz K, El-Maarouf-Bouteau H, Kranner I, Bogatek R, Corbineau F, Bailly C: The mechanisms involved in seed dormancy alleviation by unravel the role of reactive species as key factors of cellular signaling during germination. Plant Physiol. 2009 May;150(1):494-505. Epub 2009 Mar 27. This increase results from an inhibition of catalase and superoxide dismutase activities and also involves activation of oxidase. |
1(0,0,0,1) | Details |
| 19956688 | Choi J, Oh S, Lee D, Oh HJ, Park JY, Lee SB, Lim DS: Mst1-FoxO signaling protects Naive T lymphocytes from cellular oxidative stress in mice. 196-203. Interestingly, peripheral T cells from Mst1 (-/-) mice were hypersensitive to gamma-irradiation and paraquat-induced oxidative stresses, whereas those from Mst1 Tg mice were resistant. Consistently, the FoxO targets, Sod2 and catalase, were significantly down-regulated in Mst1 (-/-) T cells, thereby resulting in elevated levels of intracellular reactive species (ROS) and induction of apoptosis. |
1(0,0,0,1) | Details |
| 18436336 | Peixoto FP, Gomes-Laranjo J, Vicente JA, Madeira VM: Comparative effects of the herbicides dicamba, 2,4-D and paraquat on non-green potato tuber calli. J Plant Physiol. 2008 Jul 31;165(11):1125-33. Epub 2008 Apr 23. Paraquat induced catalase (CAT) activity at low concentrations (1 microM), whereas at higher concentrations, inhibition was observed. |
31(0,1,1,1) | Details |
| 11577197 | Yuasa T, Ichimura K, Mizoguchi T, Shinozaki K: Oxidative stress activates ATMPK6, an Arabidopsis homologue of MAP kinase. . Arch Microbiol. 2010 Mar;192(3):221-8. Epub 2010 Feb 4. In leaves, ATMPK6 was activated by paraquat and 3-amino-1,2,4-triazole (a catalase inhibitor). |
31(0,1,1,1) | Details |
| 17440995 | Li YM, Chan HY, Huang Y, Chen ZY: Green tea catechins upregulate superoxide dismutase and catalase in fruit flies. Mol Nutr Food Res. 2007 May;51(5):546-54. Supplementation of 10 mg GTC/mL diet increased the survival time only in wild type Oregon-R-C (OR) but not in two mutant fly lines, SOD (n108)/TM3 (gene for superoxide dismutase (SOD) was knocked out) and Cat (n1)/TM3 (gene for catalase was knocked out), when the flies were challenged with paraquat or peroxide. |
3(0,0,0,3) | Details |
| 18400258 | Kim J, Takahashi M, Shimizu T, Shirasawa T, Kajita M, Kanayama A, Miyamoto Y: Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans. Mech Ageing Dev. 2008 Jun;129(6):322-31. Epub 2008 Mar 2. We have shown that platinum nanoparticles (nano-Pt) are a superoxide dismutase (SOD)/catalase mimetic. Even when 0.4M paraquat was loaded exogenously, nano-Pt (0.1 and 0.5mM) and EUK-8 (0.5 and 5mM) were effective in rescuing worms. |
3(0,0,0,3) | Details |
| 15839099 | Angelova MB, Pashova SB, Spasova BK, Vassilev SV, Slokoska LS: Oxidative stress response of filamentous fungi induced by peroxide and paraquat. Mycol Res. 2005 Feb;109(Pt 2):150-8. Cell responses against both and peroxide stresses include enhanced expression of superoxide dismutase (SOD) and catalase, however, the extent was different: treatment with PQ increased mainly SOD, whereas exogenous H2O2 led to enhanced catalase. |
1(0,0,0,1) | Details |
| 17583519 | Azpilicueta CE, Benavides MP, Tomaro ML, Gallego SM: Mechanism of CATA3 induction by cadmium in sunflower leaves. Plant Physiol Biochem. 2007 Aug;45(8):589-95. Epub 2007 Apr 25. One of the main antioxidant enzymes, catalase (CAT, EC 1.11.1.6), is capable of catalyzing the dismutation of H (2) O (2). |
1(0,0,0,1) | Details |
| 11728812 | Zhou LZ, Johnson AP, Rando TA: NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells. Free Radic Biol Med. 2001 Dec 1;31(11):1405-16. We have previously shown that oxidative challenges lead to an increase in antioxidant enzymes, particularly peroxidase (GPx) and catalase (CAT), in mouse skeletal muscle. |
1(0,0,0,1) | Details |
| 10425747 | Hirai K, Pan J, Shimada H, Izuhara T, Kurihara T, Moriguchi K: Cytochemical energy-filtering transmission electron microscopy of mitochondrial free radical formation in paraquat cytotoxicity. J Electron Microsc. 1999;48(3):289-96. Precipitation reaction was scavenged by the addition of either cytochrome c or catalase and inhibited by dicoumarol (an inhibitor of NAD (P) H-quinone oxidoreductases). |
1(0,0,0,1) | Details |
| 12018841 | Park J, Ryu J, Jin LH, Bahn JH, Kim JA, Yoon CS, Kim DW, Han KH, Eum WS, Kwon HY, Kang TC, Won MH, Kang JH, Cho SW, Choi SY: 9-polylysine protein transduction domain: enhanced penetration efficiency of superoxide dismutase into mammalian cells and skin. Mol Cells. 2002 Apr 30;13(2):202-8. Antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), have been considered to have a beneficial effect against various diseases that are mediated by the reactive oxygen species (ROS). The cell viability of the fibroblast cells that were treated with paraquat, an intracellular generator, was increased by the transduced Tat-SOD or 9Lys-SOD. |
1(0,0,0,1) | Details |
| 15190189 | Joguchi A, Fujii M, Ayusawa D: Increased catalase activity in mouse cell mutants resistant to paraquat. . Biogerontology. 2004;5(3):193-200. |
13(0,0,2,3) | Details |
| 19645869 | Shopova VL, Dancheva VY, Salovsky PT, Stoyanova AM: Protective effects of a superoxide dismutase/catalase mimetic compound against paraquat pneumotoxicity in rat lung. Respirology. 2009 May;14(4):504-10. |
13(0,0,2,3) | Details |
| 11178967 | Kim HS, Lee TB, Choi CH: Down-regulation of catalase gene expression in the doxorubicin-resistant AML subline AML-2/DX100. Biochem Biophys Res Commun. 2001 Feb 16;281(1):109-14. Taken together, the paradoxical increase in the sensitivity of an MRP-overexpressing AML-2/DX100 in response to peroxides and paraquat is due to the down-regulation of catalase gene expression, which totally independent of overexpression of MRP. |
12(0,0,1,7) | Details |
| 10628300 | Lledias F, Hansberg W: Oxidation of human catalase by singlet in myeloid leukemia cells. Photochem Photobiol. 1999 Dec;70(6):887-92. Conditions that primarily generate such as treatment with paraquat or heat shock, also failed to modify the enzyme. |
12(0,0,0,12) | Details |
| 17098365 | Mehta NS, Benoit SL, Mysore J, Maier RJ: In vitro and in vivo characterization of alkyl hydroperoxide reductase mutant strains of Helicobacter hepaticus. Biochim Biophys Acta. 2007 Feb;1770(2):257-65. Epub 2006 Oct 5. Mutant strains in the tsaA gene encoding alkyl hydroperoxide reductase were more sensitive to O (2) and to oxidizing agents (paraquat, cumene hydroperoxide and t-butylhydroperoxide) than the wild type, but were markedly more resistant to peroxide. The mutant strains resistance phenotype could be attributed to a 4-fold and 3-fold increase in the catalase protein amount and activity, respectively compared to the parent strain. |
3(0,0,0,3) | Details |
| 18997852 | Koleva DI, Petrova VY, Kujumdzieva AV: Comparison of enzymatic antioxidant defence systems in different metabolic types of yeasts. Can J Microbiol. 2008 Nov;54(11):957-63. The role of antioxidant enzymes in preventing oxidant-induced cytotoxicity (treatment with peroxide, paraquat, and was shown. Twofold higher superoxide dismutase (SOD) and catalase activities were detected in K. marxianus and R. glutinis when cells were cultured on |
3(0,0,0,3) | Details |
| 16267400 | Lee SH, An CS: Differential expression of three catalase genes in hot pepper (Capsicum annuum L.). Mol Cells. 2005 Oct 31;20(2):247-55. In response to wounding and paraquat treatment, CaCat1 mRNA increased at 4-12 h in both paraquat-treated and systemic leaves. |
3(0,0,0,3) | Details |
| 19770032 | Peng C, Chan HY, Li YM, Huang Y, Chen ZY: Black tea theaflavins extend the lifespan of fruit flies. Exp Gerontol. 2009 Dec;44(12):773-83. Epub 2009 Sep 19. Gene expression of superoxide dismutase (SOD1 and SOD2), catalase (CAT), and methuselah (MTH) was characterized by an increase in young and then a decrease in aged fruit flies. Paraquat and H (2) O (2) challenge tests demonstrated that BTE prolonged the survival time only for Oregon-R wild type flies but not for SOD (n108) or Cat (n1) mutants. |
1(0,0,0,1) | Details |
| 10705509 | Hirano T, Hirobe M, Kobayashi K, Odani A, Yamauchi O, Ohsawa M, Satow Y, Nagano T: Mechanism of superoxide dismutase-like activity of Fe (II) and Fe (III) complexes of tetrakis-N,N,N',N'(2-pyridylmethyl) ethylenediamine. Chem Pharm Bull. 2000 Feb;48(2):223-30. In the cyt. c method with catalase, this Fe (III) TPEN- complex showed cyt. c oxidation activity, which had led to overestimation of its SOD activity. Chem., 264, 9243-9249 (1989)), we reported that this complex has a potent SOD activity in a cyt. c (cytochrome c)-based system (IC50 = 0.8 microM) and protects E. coli cells against paraquat toxicity. |
1(0,0,0,1) | Details |
| 10855709 | Belo I, Pinheiro R, Mota M: Response of the thermophile Thermus sp. Appl Microbiol Biotechnol. 2000 May;53(5):517-24. Cell productivity was improved by pressurisation up to 0.56 MPa for batch cultivation; and an induction of the antioxidant enzymes, superoxide dismutase and catalase, was observed with the rise in pressure. Cell pre-cultivation under pressurised conditions conferred to the cells more resistance to an exposure to peroxide and more sensitivity to paraquat (methyl viologen). |
1(0,0,0,1) | Details |
| 16580745 | Ross C, Santiago-Vazquez L, Paul V: Toxin release in response to oxidative stress and programmed cell death in the cyanobacterium Microcystis aeruginosa. Aquat Toxicol. 2006 Jun 10;78(1):66-73. Epub 2006 Apr 3. Despite the fact that secreted toxin levels were relatively low in dense natural assemblages (3.5 microg l (-1)), detectable toxin levels increased by 90% when M. aeruginosa was stressed by an increase in salinity, physical injury, application of the chemical herbicide paraquat, or UV irradiation. Catalase was capable of inhibiting PCD, implicating H (2) O (2) as the inducing oxidative species. |
1(0,0,0,1) | Details |
| 12826488 | Schmuck G, Rohrdanz E, Tran-Thi QH, Kahl R, Schluter G: Oxidative stress in rat cortical neurons and astrocytes induced by paraquat in vitro. Neurotox Res. 2002 Feb;4(1):1-13. Paraquat exposure lead to a 2-3 fold increase of catalase, MnSOD and CuZnSOD mRNA expression in astrocytes. |
12(0,0,2,2) | Details |
| 11728823 | Jin LH, Bahn JH, Eum WS, Kwon HY, Jang SH, Han KH, Kang TC, Won MH, Kang JH, Cho SW, Park J, Choi SY: Transduction of human catalase mediated by an HIV-1 TAT protein basic domain and -rich peptides into mammalian cells. Free Radic Biol Med. 2001 Dec 1;31(11):1509-19. In combination with transduced SOD, transduced catalase also resulted in a cooperative increase in cell viability when the cells were treated with paraquat, an intracellular antioxide anion generator. |
11(0,0,1,6) | Details |
| 11325355 | Rohrdanz E, Schmuck G, Ohler S, Kahl R: The influence of oxidative stress on catalase and MnSOD gene transcription in astrocytes. Brain Res. 2001 May 4;900(1):128-36. Transient transfection of primary astroglial cells with a reporter plasmid containing the upstream region of the catalase gene showed a decrease in reporter gene activity after exposure of transfected cells to either H2O2 or paraquat. |
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| 19767862 | Beltran-Garcia MJ, Manzo-Sanchez G, Guzman-Gonzalez S, Arias-Castro C, Rodriguez-Mendiola M, Avila-Miranda M, Ogura T: Oxidative stress response of Mycosphaerella fijiensis, the causal agent of black leaf streak disease in banana plants, to peroxide and paraquat. Can J Microbiol. 2009 Jul;55(7):887-94. Two active catalase bands were seen in native PAGE induced by H2O2. |
3(0,0,0,3) | Details |
| 14555815 | Hong SY, Yang JO, Lee EY, Lee ZW: Effects of N-acetyl- and on antioxidant status of human serum and 3T3 fibroblasts. J Biol Chem. 1999 May 7;274(19):13650-5. The effectiveness of several sulfhydryl compounds in the treatment of paraquat intoxication has been previously tested based on their antioxidant ability. As a preliminary pharmacokinetic study on sulfhydryl compounds, we attempted to establish the optimal concentration of N-acetyl- superoxide dismutase, and catalase. |
3(0,0,0,3) | Details |
| 18686095 | Ullmann K, Wiencierz AM, Muller C, Thierbach R, Steege A, Toyokuni S, Steinberg P: A high-throughput reporter gene assay to prove the ability of natural compounds to modulate peroxidase, superoxide dismutase and catalase gene promoters in V79 cells. Free Radic Res. 2008 Aug;42(8):746-53. Thereafter the ability of paraquat, 12-O-tetradecanoylphorbol-13- and Trolox to enhance the promoter activities was evaluated. |
3(0,0,0,3) | Details |
| 17080932 | Zimmermann P, Heinlein C, Orendi G, Zentgraf U: Senescence-specific regulation of catalases in Arabidopsis thaliana (L.) Heynh. Plant Cell Environ. 2006 Jun;29(6):1049-60. |
2(0,0,0,2) | Details |
| 10754530 | Suzuki Y, Kondo Y, Himeno S, Nemoto K, Akimoto M, Imura N: Role of antioxidant systems in human androgen-independent prostate cancer cells. Prostate. 2000 May 1;43(2):144-9. METHODS: Three cell lines of human hormone-independent prostate cancer (PC-3, PC-3 MA2, and HPC36M) were examined for activities of superoxide dismutase, catalase, and peroxidase, and for levels of protein and nonprotein thiols such as metallothionein, and thioredoxin. Sensitivity of these cells to anticancer drugs and inducers of reactive species such as paraquat, tert-butylhydroperoxide, and peroxide was determined by microtiter assay. |
2(0,0,0,2) | Details |
| 20002190 | Italiani VC, Braz VS, Xiao H, Steinman HM, Marques MV: Catalase-peroxidase activity is decreased in a Caulobacter crescentus rho mutant. FEMS Microbiol Lett. 2009 Nov 23. The mutant was shown to be permanently under oxidative stress, based on fluorophore oxidation, and also to be sensitive to tert-butyl hydroperoxide and paraquat. |
1(0,0,0,1) | Details |
| 18074631 | Spiegelman BM: Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found Symp. 2007;287:60-3; discussion 63-9. This includes genes encoding mitochondrial proteins like SOD2, but also includes cytoplasmic proteins such as catalase and GPX1. Cells lacking PGC1alpha are hypersensitive to death from oxidative stress caused by H2O2 or paraquat. |
1(0,0,0,1) | Details |
| 20131044 | Roehrs R, Freitas DR, Masuda A, Henriques JA, Guecheva TN, Ramos AL, Saffi J: Effect of treatment on superoxide dismutase-deficient yeast strains. Pharmacol Toxicol. 2000 Mar;86(3):102-9. Possible adaptation effects induced by sub-lethal oxidative stress were monitored by pre-, co- and post-treatment with the oxidative agent paraquat. The enzymatic activities of catalase (CAT) and peroxidase (GPx), and the total content were determined after Vit A treatment. |
1(0,0,0,1) | Details |
| 19763183 | Cantu D, Schaack J, Patel M: Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures. PLoS One. 2009 Sep 18;4(9):e7095. METHODOLOGY/PRINCIPAL FINDINGS: Incubation of rat primary mesencephalic cultures with the redox cycling herbicide paraquat (PQ2+) resulted in increased production of H2O2 and Fe2+ at times preceding cell death. Increased cell death in m-aconitase overexpressing cultures was attenuated by addition of catalase and/or a cell permeable iron chelator suggesting that neuronal death occurred in part via astrocyte-derived H2O2. |
1(0,0,0,1) | Details |
| 15312845 | Soler-Garcia AA, Jerse AE: A Neisseria gonorrhoeae catalase mutant is more sensitive to peroxide and paraquat, an inducer of toxic radicals. Microb Pathog. 2004 Aug;37(2):55-63. |
10(0,0,1,5) | Details |
| 19404744 | Lee DH, Oh KH, Kahng HY: Molecular analysis of antioxidant genes in the extremohalophile marine bacterium Exiguobacterium sp. Biotechnol Lett. 2009 Aug;31(8):1245-51. Epub 2009 Apr 29. RT-PCR-based expression analysis at the transcriptional level suggested that the catalase gene is strongly expressed in response to 2 mM H (2) O (2), 0.2 mM Paraquat and 0.2 mM |
9(0,0,1,4) | Details |
| 10913087 | Ochsner UA, Vasil ML, Alsabbagh E, Parvatiyar K, Hassett DJ: Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF. J Bacteriol. 2000 Aug;182(16):4533-44. The oxyR mutant was hypersusceptible to oxidative stress-generating agents, including H (2) O (2) and paraquat, in spite of total KatA catalase activity being comparable to that of the wild type. |
8(0,0,1,3) | Details |
| 14641049 | Sampayo JN, Gill MS, Lithgow GJ: Oxidative stress and aging--the use of superoxide dismutase/catalase mimetics to extend lifespan. Biochem Soc Trans. 2003 Dec;31(Pt 6):1305-7. These compounds also appear to confer resistance to oxidative damage, since they protect against paraquat treatment. |
2(0,0,0,2) | Details |
| 10218660 | Tate DJ Jr, Miceli MV, Newsome DA: protects against oxidative damage in cultured human retinal pigment epithelial cells. Free Radic Biol Med. 1999 Mar;26(5-6):704-13. After 1 week, MTT assays were performed to determine the relative cytotoxicity of H2O2 or paraquat on RPE cells. The antioxidants metallothionein, catalase, superoxide dismutase, and peroxidase were also measured. |
2(0,0,0,2) | Details |
| 11154047 | Kim JS, Na CS, Pak SC, Kim YG: Effects of yukmi, an herbal formula, on the liver of senescence accelerated mice (SAM) exposed to oxidative stress. Am J Chin Med. 2000;28(3-4):343-50. The effects of yukmi (Decoction of six plants including rehmannia), an herbal formula, were studied on liver oxidant damage induced by paraquat (PQ) administered intravenously in the senescence accelerated mice (SAM-P/8). The activities of superoxide dismutase (SOD) and catalase as two major antioxidant enzymes and lipid peroxidation levels were determined for six days. |
2(0,0,0,2) | Details |
| 20095325 | Huang M, Zhang P, Chang XL, Wu Q, Zhou ZJ: [Change of oxidative stress and nuclear factor-kappa B in acute paraquat poisoned rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Aug;27(8):457-62. On the 1st, the 3rd, the 7th, the 14th, the 28th and the 56th day after treatment, the level of malondialdehyde (MDA), the activity of peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT) and myeloperoxidase (MPO) in serum were detected; the content of (Hyp) and the activity of NF-kappaB in lung tissues were detected; the lung pathological changes of rats were observed. |
1(0,0,0,1) | Details |
| 11386371 | Santos R, Franza T, Laporte ML, Sauvage C, Touati D, Expert D: Essential role of superoxide dismutase on the pathogenicity of Erwinia chrysanthemi strain 3937. Mol Plant Microbe Interact. 2001 Jun;14(6):758-67. If the inoculum was supplemented with the -scavenging metalloporphyrin MnTMPyP or purified SOD and catalase, the deltasodA mutant was able to macerate the inoculated zone. The deltasodA mutant was more sensitive to paraquat than the wild-type strain. |
1(0,0,0,1) | Details |
| 17107770 | Ghazi-Khansari M, Mohammadi-Bardbori A: Captopril ameliorates toxicity induced by paraquat in mitochondria isolated from the rat liver. Toxicol In Vitro. 2007 Apr;21(3):403-7. Epub 2006 Oct 10. Lipid peroxidation, catalase activity, GSH and concentrations were determined in isolated rat liver mitochondria. |
1(0,0,0,1) | Details |
| 15500464 | Park EJ, Jeknic Z, Sakamoto A, DeNoma J, Yuwansiri R, Murata N, Chen TH: Genetic engineering of glycinebetaine synthesis in tomato protects seeds, plants, and flowers from chilling damage. Plant J. 2004 Nov;40(4):474-87. Exogenous application of either GB or H2O2 improves both chilling and oxidative tolerance concomitant with enhanced catalase activity. |
1(0,0,0,1) | Details |
| 18849295 | Colville L, Smirnoff N: Antioxidant status, peroxidase activity, and PR protein transcript levels in -deficient Arabidopsis thaliana vtc mutants. J Exp Bot. 2008;59(14):3857-68. Epub 2008 Oct 9. Endochitinase transcript levels increased after paraquat, and UV-C treatment, PR1 after treatment, and PR2 after paraquat and UV-C treatment. |
0(0,0,0,0) | Details |
| 16677106 | Mele J, Van Remmen H, Vijg J, Richardson A: Characterization of transgenic mice that overexpress both zinc superoxide dismutase and catalase. Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):628-38. The MEFs from Tg (SOD1/CAT) +/o tended to be more resistant (up to 2.25-fold) to paraquat cytotoxicity than MEFs overexpressing either Cu/ZnSOD or catalase alone. |
8(0,0,1,3) | Details |
| 10751631 | Schriner SE, Smith AC, Dang NH, Fukuchi K, Martin GM: Overexpression of wild-type and nuclear-targeted catalase modulates resistance to oxidative stress but does not alter spontaneous mutant frequencies at APRT. Mutat Res. 2000 Apr 3;449(1-2):21-31. Overexpression of wild-type catalase protected cells against paraquat, while nuclear targeting sensitized them to this agent. |
8(0,0,1,3) | Details |
| 19777209 | Todorova TT, Petrova VY, Vuilleumier S, Kujumdzieva AV: Response to different oxidants of Saccharomyces cerevisiae ure2Delta mutant. Arch Microbiol. 2009 Nov;191(11):837-45. Epub 2009 Sep 24. Data for the lack of significant effect of URE2 disruption on the cellular growth in the presence of paraquat and were obtained. The important role of Ure2p in in vivo -mediated reactive species (ROS) scavenging was shown by measuring the activity of antioxidant enzymes peroxidase, superoxide dismutase (SOD) and catalase in an URE2 disrupted strain. |
2(0,0,0,2) | Details |
| 18235974 | Chen P, Li A, Zhang M, He M, Chen Z, Wu X, Zhao C, Wang S, Liang L: Protective effects of a new metalloporphyrin on paraquat-induced oxidative stress and apoptosis in N27 cells. Acta Biochim Biophys Sin. 2008 Feb;40(2):125-32. In this study, we examined the neuroprotective effect of (III) meso-tetrakis (N,N'-diethylimidazolium) (MnTDM), a superoxide dismutase/catalase mimetic, on PQ-induced oxidative stress and apoptosis in 1RB3AN27 (N27) cells, a dopaminergic neuronal cell line. |
1(0,0,0,1) | Details |
| 11379772 | Sasaki N, Baba N, Matsuo M: Cytotoxicity of reactive species and related agents toward undifferentiated and differentiated rat phenochromocytoma PC12 cells. Biol Pharm Bull. 2001 May;24(5):515-9. These species and agents include peroxide, hydroperoxide (LOOH), tert-butyl hydroperoxide, paraquat, 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH), 2,2'-azobis (2,4-dimethylvaleronitrile) (AMVN), and a -xanthine oxidase system. The peroxidase activity level of the undifferentiated cells was 2-3 times higher than the differentiated cells, the catalase activity level also tended to be higher, the superoxide dismutase activity level was higher on -protein-quantity basis but lower on -cell-number basis, and the total and concentration levels were considerably higher. |
1(0,0,0,1) | Details |
| 10501032 | Wang J, Zhang H, Allen RD: Overexpression of an Arabidopsis peroxisomal peroxidase gene in tobacco increases protection against oxidative stress. Plant Cell Physiol. 1999 Jul;40(7):725-32. The expression of APX3 in tobacco could protect leaves from oxidative stress damage caused by aminotriazole which inhibits catalase activity that is found mainly in glyoxysomes and peroxisomes and leads to accumulation of H2O2 in those organelles. However, these plants did not show increased protection from oxidative damage caused by paraquat which leads to the production of reactive species in chloroplasts. |
1(0,0,0,1) | Details |
| 19135146 | James BP, Staatz WD, Wilkinson ST, Meuillet E, Powis G: Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells. Free Radic Biol Med. 2009 Mar 15;46(6):821-7. Epub 2008 Dec 24. In the fission yeast, Schizosaccharomyces pombe, the LAMMER kinase gene, Lkh1, positively regulates the expression of the antioxidant defense genes, superoxide dismutase 1 (sod1+, CuZn-SOD) and catalase (ctt1+, CAT). We have shown that mutations in the Drosophila LAMMER kinase gene, Darkener of apricot (Doa), protect against the decrease in life span caused by the reactive species (ROS) generator paraquat, and at the same time show an increase in cytoplasmic (CuZn-Sod or SOD1) and mitochondrial superoxide dismutase (Mn-Sod or SOD2) protein levels and activity. |
1(0,0,0,1) | Details |
| 11039594 | Kiyomiya K, Matsushita N, Matsuo S, Kurebe M: Roles of radical production and lipid peroxidation in the cytotoxicity of cephaloridine on cultured renal epithelial cells (LLC-PK1). J Vet Med Sci. 2000 Sep;62(9):977-81. CER increased the content of peroxide and decreased the activity of catalase in the treated cells, followed by an increase in the content of lipid peroxide and decreases in both peroxidase activity and in the non-protein sulfhydryl content. The levels of -dependent peroxide and production by microsomes prepared from LLC-PK1 cells, and by -cytochrome P-450 reductase purified from the rat renal cortex were significantly increased by paraquat. |
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| 11264896 | Tomita M, Okuyama T, Ishikawa T, Hidaka K, Nohno T: The role of in paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line. Free Radic Res. 2001 Feb;34(2):193-202. |
0(0,0,0,0) | Details |
| 15530657 | Chen L, Rio DC, Haddad GG, Ma E: Regulatory role of dADAR in ROS metabolism in Drosophila CNS. Brain Res Mol Brain Res. 2004 Nov 24;131(1-2):93-100. Recently, we found that the mutant flies were very resistant to paraquat, a compound that generates free radicals. |
0(0,0,0,0) | Details |
| 10986229 | King KY, Horenstein JA, Caparon MG: Aerotolerance and peroxide resistance in peroxidase and PerR mutants of Streptococcus pyogenes. J Bacteriol. 2000 Oct;182(19):5290-9. However, they were more susceptible than the wild type to growth suppression by paraquat and cumene hydroperoxide. |
0(0,0,0,0) | Details |
| 17220179 | Ungvari Z, Orosz Z, Rivera A, Labinskyy N, Xiangmin Z, Olson S, Podlutsky A, Csiszar A: increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2417-24. Epub 2007 Jan 12. Indeed, treatment protected cultured aortic segments and/or endothelial cells against increases in intracellular H (2) O (2) levels and H (2) O (2)-mediated apoptotic cell death induced by oxidative stressors (exogenous H (2) O (2), paraquat, and UV light). |
0(0,0,0,0) | Details |
| 10705040 | Nestelbacher R, Laun P, Vondrakova D, Pichova A, Schuller C, Breitenbach M: The influence of oxygen toxicity on yeast mother cell-specific aging. Exp Gerontol. 2000 Feb;35(1):63-70. The effect of deleting both catalase genes and of increased as well as paraquat (a pro-oxidant) on the replicative life span of yeast mother cells has been investigated to test the so-called theory of aging. |
8(0,0,1,3) | Details |
| 15101064 | Klichko VI, Radyuk SN, Orr WC: Profiling catalase gene expression in Drosophila melanogaster during development and aging. Arch Insect Biochem Physiol. 2004 May;56(1):34-50. Finally, when adult flies were subjected to various environmental insults, such as heat, paraquat, hyperoxia and H (2) O (2), no significant responses were observed, suggesting that catalase gene expression is largely governed by intrinsic genetic programs. |
7(0,0,0,7) | Details |
| 12422520 | Asma D, Yesilada O: Effect of paraquat on cellular defense enzymes and level of Funalia trogii. Folia Microbiol. 2002;47(4):413-6. Paraquat treatment probably depresses antioxidant defense components such as catalase and |
7(0,0,1,2) | Details |
| 14677634 | Sampayo JN, Olsen A, Lithgow GJ: Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics. Aging Cell. 2003 Dec;2(6):319-26. Here we demonstrate that the mimetics, Euk-134 and Euk-8, confer resistance to the oxidative stress-inducing agent, paraquat and to thermal stress. |
2(0,0,0,2) | Details |
| 15878237 | Chen ZH, Yoshida Y, Saito Y, Niki E: Adaptation to peroxide enhances PC12 cell tolerance against oxidative damage. Neurosci Lett. 2005 Aug 5;383(3):256-9. The endogenous antioxidant defense systems, catalase and peroxidase, were enhanced quickly by the pretreatment of low doses of H2O2. This pretreatment also exerted protective effect against the oxidative insults induced by and paraquat, but not against alkyl peroxyl radicals. |
1(0,0,0,1) | Details |
| 11557130 | Lehmann T, Kohler C, Weidauer E, Taege C, Foth H: Expression of MRP1 and related transporters in human lung cells in culture. Toxicology. 2001 Oct 5;167(1):59-72. AII cells exhibited low basal levels of mdr1b mRNA, that increased over time and after radical production induced by paraquat. mRNAs coding for antioxidative enzymes catalase (CAT), maganese superoxide dismutase (Mn-SOD) and /zinc superoxide dismutase (Cu/Zn-SOD) were not changed. |
0(0,0,0,0) | Details |
| 16919916 | Mitra S, Abraham E: Participation of in neutrophil activation and cytokine production. Biochim Biophys Acta. 2006 Aug;1762(8):732-41. Epub 2006 Jul 8. To examine the role of in neutrophil activation, we exposed resting neutrophils and neutrophils stimulated with LPS to paraquat, an agent that specifically increases intracellular concentrations. |
0(0,0,0,0) | Details |
| 10699569 | Ali S, Diwakar G, Pawa S: Paraquat induces different pulmonary biochemical responses in Wistar rats and Swiss mice. Chem Biol Interact. 2000 Mar 1;125(2):79-91. It is implied that an early induction of catalase in mice as opposed to rats may account for the resistance of Swiss mice to paraquat toxicity. |
7(0,0,1,2) | Details |
| 17935786 | Olesen BT, Clausen J, Vang O: Characterization of the transcriptional profile in primary astrocytes after oxidative stress induced by Paraquat. Neurotoxicology. 2008 Jan;29(1):13-21. Epub 2007 Sep 1. Paraquat induced the expression of Mn- and CuZn SOD, catalase and decreases the expression of c-jun (a part of AP-1). |
7(0,0,1,2) | Details |
| 10959798 | Rohrdanz E, Obertrifter B, Ohler S, Tran-Thi QH, Kahl R: Influence of Adriamycin and paraquat on antioxidant enzyme expression in primary rat hepatocytes. Arch Toxicol. 2000 Jul;74(4-5):231-7. In contrast, exposure of hepatocytes to paraquat resulted in an increase in both catalase and MnSOD message levels. |
7(0,0,1,2) | Details |
| 12521602 | Mockett RJ, Bayne AC, Kwong LK, Orr WC, Sohal RS: Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. Free Radic Biol Med. 2003 Jan 15;34(2):207-17. Catalase, an antioxidative enzyme expressed in the cytosol and peroxisomes of Drosophila, was targetted ectopically to the mitochondrial matrix by fusion of a leader peptide derived from ornithine aminotransferase with its N-terminus. Resistance to exogenous peroxide, paraquat, and cold stress was enhanced, but there was no appreciable effect on resistance to hyperoxia. |
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| 16735730 | Brioukhanov AL, Netrusov AI, Eggen RI: The catalase and superoxide dismutase genes are transcriptionally up-regulated upon oxidative stress in the strictly anaerobic archaeon Methanosarcina barkeri. Microbiology. 2006 Jun;152(Pt 6):1671-7. The oxidative stress agent paraquat (PQ) suppressed growth of M. barkeri at concentrations of 50-200 microM. |
2(0,0,0,2) | Details |
| 20116453 | Farmen E, Olsvik PA, Berntssen MH, Hylland K, Tollefsen KE: Oxidative stress responses in rainbow trout (Oncorhynchus mykiss) hepatocytes exposed to pro-oxidants and a complex environmental sample. Comp Biochem Physiol C Toxicol Pharmacol. 2010 May;151(4):431-8. Epub 2010 Jan 28. The pro-oxidants CuSO (4) and paraquat were used as models for comparison to a complex environmental sample. Results following 6, 24, 48 and 96h exposure to different concentrations of these substances show cellular effects on intracellular ROS formation, levels and redox status, expression of the antioxidant enzymes superoxide dismutase, catalase, peroxidase, glutathione reductase, gamma-glutamyl- synthetase (GCS) and thioredoxin, as well as cytotoxicity parameters. |
2(0,0,0,2) | Details |
| 11875618 | Hoet PH, Roesems G, Demedts MG, Nemery B: Activation of the hexose monophosphate shunt in rat type II pneumocytes as an early marker of oxidative stress caused by particles. Arch Toxicol. 2002 Feb;76(1):1-7. Epub 2002 Jan 12. The observed time course of the activation by mCo particles clearly differed from that caused by paraquat (10 (-5 ) M), which is known to produce activated species after cyclic oxidation-reduction reactions. The comparable effect of peroxides (H2O2 and t-butyl hydroperoxide) on HMS and the inhibitory effects of catalase on the mCo-induced stimulation of the HMS strongly suggest the production of peroxides by freshly immersed mCo particles. |
1(0,0,0,1) | Details |
| 12383513 | Loprasert S, Sallabhan R, Whangsuk W, Mongkolsuk S: The Burkholderia pseudomallei oxyR gene: expression analysis and mutant characterization. Gene. 2002 Aug 21;296(1-2):161-9. It is located between recG, encoding a putative DNA helicase, and katG, encoding a putative catalase-peroxidase. oxyR is expressed as a monocistronic 1 kb mRNA and is induced by oxidative stress compounds. Northern, primer extension, and transcription reporter fusion analyses showed that oxyR mRNA is induced by 0.2 mM 2 mM paraquat, and 10 mM H (2) O (2). |
1(0,0,0,1) | Details |
| 10679488 | Drummond GR, Cai H, Davis ME, Ramasamy S, Harrison DG: Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by peroxide. Circ Res. 2000 Feb 18;86(3):347-54. Exposure of bovine aortic endothelial cells for 24 hours to paraquat, a (O (2)(-*))-generating compound, did not affect eNOS mRNA levels. |
0(0,0,0,0) | Details |
| 10910079 | Siemankowski LM, Morreale J, Butts BD, Briehl MM: Increased tumor necrosis factor-alpha sensitivity of MCF-7 cells transfected with NAD (P) H:quinone reductase. Cancer Res. 2000 Jul 1;60(13):3638-44. This increased sensitivity could not be explained by changes in superoxide dismutase or catalase activity or to increased sensitivity to oxidative stress in general, as assessed by response to peroxide and paraquat treatment. |
0(0,0,0,0) | Details |
| 15907763 | Barata C, Varo I, Navarro JC, Arun S, Porte C: Antioxidant enzyme activities and lipid peroxidation in the freshwater cladoceran Daphnia magna exposed to redox cycling compounds. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Feb;140(2):175-86. Epub 2005 Feb 24. Activities of key antioxidant enzymes including catalase, superoxide dismutase, peroxidase and glutathione S-transferases and levels of lipid peroxidation measured as thiobarbituric acid-reactive substances (TBARS) and lipofucsin pigment content were determined in D. magna juveniles after being exposed to sublethal levels of paraquat, endosulfan, cadmium and for 48 h. |
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| 19377883 | Qian H, Chen W, Sun L, Jin Y, Liu W, Fu Z: Inhibitory effects of paraquat on photosynthesis and the response to oxidative stress in Chlorella vulgaris. Ecotoxicology. 2009 Jul;18(5):537-43. Epub 2009 Apr 18. Exposure to 0.5 microM paraquat increased the activities of the antioxidant enzymes superoxide dismutase, peroxidase, and catalase to levels 4.93, 3.19, and 3.09 times higher, respectively, than those of the control. |
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| 14581623 | Fukamatsu Y, Yabe N, Hasunuma K: Arabidopsis NDK1 is a component of ROS signaling by interacting with three catalases. Plant Cell Physiol. 2003 Oct;44(10):982-9. Transgenic plants expressing AtNDK1 under control of the CaMV 35S promoter exhibited tolerance to paraquat and high ability to eliminate exogenous H2O2. |
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| 17349929 | Dinis-Oliveira RJ, Sousa C, Remiao F, Duarte JA, Navarro AS, Bastos ML, Carvalho F: Full survival of paraquat-exposed rats after treatment with Free Radic Biol Med. 2007 Apr 1;42(7):1017-28. Epub 2007 Jan 8. In addition, histopathological lesions induced by PQ in lung were strongly attenuated and the oxidant-induced increases of peroxidase and catalase expression became absent. |
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| 18985485 | Ahmad I, Kumar A, Shukla S, Prasad Pandey H, Singh C: The involvement of in maneb- and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes. Free Radic Res. 2008 Oct;42(10):849-62. A significant increase in myeloperoxidase (MPO), superoxide dismutase (SOD), iNOS expression and lipid peroxidation (LPO) was observed in PMNs of MB- and/or PQ-treated animals, while catalase and glutathione S-transferase (GST) activities were attenuated. |
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| 12559405 | Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, Van Eygen S, Vanfleteren JR: No reduction of metabolic rate in food restricted Caenorhabditis elegans. Exp Gerontol. 2002 Dec;37(12):1359-69. The specific activity levels of the antioxidant enzymes superoxide dismutase (SOD) and catalase showed small increases when we reduced food in wild-type worms, but restricted worms acquired no elevated protection against paraquat and peroxide. eat-2 mutants showed elevated specific activities of SOD and catalase relative to wild type in liquid culture. |
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| 12732627 | Wang X, Phelan SA, Forsman-Semb K, Taylor EF, Petros C, Brown A, Lerner CP, Paigen B: Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress. J Biol Chem. 2003 Jul 4;278(27):25179-90. Epub 2003 May 5. To determine these functions, we generated Prdx6-targeted mutant (Prdx6-/-) mice, confirmed the gene disruption by Southern blots, PCR, RT-PCR, Western blots, and immunohistochemistry, and compared the effects of paraquat, peroxide, and t-butyl hydroperoxide on Prdx6-/- and wild-type (Prdx6+/+) macrophages, and of paraquat on Prdx6-/- and Prdx6+/+ mice. |
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| 12180188 | Noriega GO, Gonzales S, Tomaro ML, Batlle AM: Paraquat-generated oxidative stress in rat liver induces heme oxygenase-1 and synthase. Free Radic Res. 2002 Jun;36(6):633-9. The activity of liver antioxidant enzymes, superoxide dismutase, catalase and peroxidase was decreased 3 h after paraquat injection. |
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| 16195250 | Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W: Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Mol Endocrinol. 2006 Feb;20(2):279-90. Epub 2005 Sep 29. The PXR-induced paraquat sensitivity was associated with decreased activities of superoxide dismutase and catalase, enzymes that scavenge and peroxide, respectively. |
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| 15871734 | Sturve J, Stephensen E, Forlin L: Effects of redox cycling compounds on DT diaphorase activity in the liver of rainbow trout (Oncorhynchus mykiss). Comp Hepatol. 2005 May 4;4(1):4. In addition, the effect of short term exposure to prooxidants on catalase activity was investigated. RESULTS: In rainbow trout, hepatic DTD activity is induced by the bifunctional AHR agonists beta-NF and B (a) P and the monofunctional inducers naphthazarin, and paraquat. |
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| 10416023 | Schultz JR, Clarke CF: Characterization of Saccharomyces cerevisiae -deficient mutants. Biofactors. 1999;9(2-4):121-9. Superoxide dismutase (SOD) activity decreased and catalase activity increased in both Q-deficient and atp2 delta mutants compared to wild-type cells, suggesting that such changes result from the loss of respiration rather than the lack of Q. |
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| 12028379 | Horsburgh MJ, Wharton SJ, Cox AG, Ingham E, Peacock S, Foster SJ: MntR modulates expression of the PerR regulon and resistance in Staphylococcus aureus through control of uptake. Mol Microbiol. 2002 Jun;44(5):1269-86. The expression of the PerR-regulated genes, katA (catalase), ftn (ferritin) and fur (ferric uptake regulator), was diminished in STE031 (mntR) when grown in excess Mn (II). |
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| 10228384 | Niwa Y: [Oxidative injury and its defense system in vivo] . Rinsho Byori. 1999 Mar;47(3):189-209. Recently, it was reported that environmental toxic agents including herbicides such as paraquat, insecticides, and ultraviolet radiation produce free radicals. On the other hand, a self-defense system exists against oxidative injuries; high-molecular-weight antioxidants such as SOD, catalase, and GSH-Px, and low-molecular-weight antioxidants such as E, A, polyphenols, flavonoids, and |
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| 15479627 | Choi DG, Yoo NH, Yu CY, de Los Reyes B, Yun SJ: The activities of antioxidant enzymes in response to oxidative stresses and hormones in paraquat-tolerant Rehmannia glutinosa plants. J Biochem Mol Biol. 2004 Sep 30;37(5):618-24. However, the activity of catalase (CAT) was about 12-fold higher in the soybeans. |
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| 11447191 | Poyart C, Pellegrini E, Gaillot O, Boumaila C, Baptista M, Trieu-Cuot P: Contribution of Mn-cofactored superoxide dismutase (SodA) to the virulence of Streptococcus agalactiae. Infect Immun. 2001 Aug;69(8):5098-106. Superoxide dismutases convert anions to molecular and peroxide, which, in turn, is metabolized by catalases and/or peroxidases. The growth rates of these strains in standing cultures were comparable, but the sodA mutant was extremely susceptible to the oxidative stress generated by addition of paraquat or peroxide to the culture medium and exhibited a higher mutation frequency in the presence of rifampin. |
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| 16510128 | Patel S, Singh V, Kumar A, Gupta YK, Singh MP: Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration. Brain Res. 2006 Apr 7;1081(1):9-18. Epub 2006 Feb 28. A significant increase in catalase, glutathione S-transferase and lipid peroxidation in the striatum was found following 3, 6 and 9 weeks of co-treatment as compared with individual treatment or controls. |
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| 12803620 | Jiang M, Zhang J: Cross-talk between and reactive species originated from oxidase in abscisic acid-induced antioxidant defence in leaves of maize seedlings. Plant Cell Environ. 2003 Jun;26(6):929-939. Treatment with ABA led to significant increases in the activity of plasma membrane oxidase, the production of leaf O2-, and the activities of several antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), peroxidase (APX) and glutathione reductase (GR). Treatment with oxidative stress induced by paraquat, which generates O2-, led to the induction of antioxidant defence enzymes, and the up-regulation was suppressed by the pretreatment of Ca2+ chelator and Ca2+ channel blockers. |
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| 15501432 | Dafre AL, Medeiros ID, Muller IC, Ventura EC, Bainy AC: Antioxidant enzymes and thiol/disulfide status in the digestive gland of the brown mussel Perna perna exposed to lead and paraquat. Chem Biol Interact. 2004 Oct 15;149(2-3):97-105. We were unable to detect an effect of Pb treatment on the enzymes, catalase, glucose 6-phosphate dehydrogenase (G6PDH), glutathione S-transferase (GST) and glutathione reductase -reductase), which contrasts to the effect of PQ, increasing -reductase and G6PDH, but decreasing GST activity. |
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| 12432032 | Jiang M, Zhang J: Water stress-induced abscisic acid accumulation triggers the increased generation of reactive species and up-regulates the activities of antioxidant enzymes in maize leaves. Arch Biochem Biophys. 2004 Feb 15;422(2):197-210. The interrelationship among water-stress-induced abscisic acid (ABA) accumulation, the generation of reactive species (ROS), and the activities of several antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), peroxidase (APX), and glutathione reductase (GR) was investigated in leaves of detached maize (Zea mays L.) plants exposed to -0.7 MPa water stress induced by polyethylene glycol (PEG 6000). A mild oxidative stress induced by paraquat, which generates O (2)(-) and then H (2) O (2), resulted in a significant enhancement in the activities of antioxidant enzymes in non-water-stressed leaves. |
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| 19634056 | Schriner SE, Abrahamyan A, Avanessian A, Bussel I, Maler S, Gazarian M, Holmbeck MA, Jafari M: Decreased mitochondrial levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea. Free Radic Res. 2009 Sep;43(9):836-43. Epub 2009 Jul 24. |
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| 12021807 | Pinheiro R, Belo I, Mota M: Oxidative stress response of Kluyveromyces marxianus to peroxide, paraquat and pressure. Appl Microbiol Biotechnol. 2002 May;58(6):842-7. Epub 2002 Feb 8. |
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| 10224137 | Lin KI, Pasinelli P, Brown RH, Hardwick JM, Ratan RR: Decreased intracellular levels activate Sindbis virus-induced apoptosis. 162-3 Moreover, increasing intracellular O-2 by treatment of 3T3 cells with paraquat protects them from SV-induced death. |
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| 10844693 | Kehres DG, Zaharik ML, Finlay BB, Maguire ME: The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective transporters involved in the response to reactive Mol Microbiol. 2000 Jun;36(5):1085-100. In both S. typhimurium and E. coli, mntH:lacZ constructs were strongly induced by peroxide, weakly induced by EDTA and unresponsive to paraquat, consistent with the presence of Fur and OxyR binding sites in the promoters. |
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| 15177642 | Weidauer E, Lehmann T, Ramisch A, Rohrdanz E, Foth H: Response of rat alveolar type II cells and human lung tumor cells towards oxidative stress induced by peroxide and paraquat. Toxicol Lett. 2004 Jun 15;151(1):69-78. Only 50 microM paraquat induced a significant decrease in catalase activity and an increase in Cu/Zn-SOD activity. |
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| 17196654 | Cochon AC, Della Penna AB, Kristoff G, Piol MN, San Martin de Viale LC, Verrengia Guerrero NR: Differential effects of paraquat on oxidative stress parameters and polyamine levels in two freshwater invertebrates. Ecotoxicol Environ Saf. 2007 Oct;68(2):286-92. Epub 2006 Dec 29. The aim of this work was to investigate some aspects related to paraquat-induction of oxidative stress (lipoperoxidation, enzymatic activities of catalase and superoxide dismutase) and also the levels of polyamines and in two species of freshwater invertebrates, the oligochaete Lumbriculus variegatus and the gastropod Biomphalaria glabrata. |
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| 17712041 | Shuvaev VV, Tliba S, Nakada M, Albelda SM, Muzykantov VR: Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular J Pharmacol Exp Ther. 2007 Nov;323(2):450-7. Epub 2007 Aug 21. Targeting of the antioxidant enzyme catalase to endothelial cells protects against vascular oxidative stress induced by peroxide (H (2) O (2))(Am J Physiol 285:L283-L292, 2003; Nat Biotechnol 21:392-398, 2003; Am J Physiol 293:L162-L169, 2007). In the second model, anti-PECAM/SOD at the optimal dose provided complete protection against necrosis caused by paraquat-induced intracellular generation. |
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| 16162242 | Abrashev R, Dolashka P, Christova R, Stefanova L, Angelova M: Role of antioxidant enzymes in survival of conidiospores of Aspergillus niger 26 under conditions of temperature stress. J Appl Microbiol. 2005;99(4):902-9. AIMS: A better understanding of the role of antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) in the protection of Aspergillus niger spores against thermal stress. We compared the influence of heat shock and -generating agent paraquat on growth and antioxidant enzyme defence and found different response to the both type of stresses. |
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| 14658382 | Yu T, Li YS, Chen XF, Hu J, Chang X, Zhu YG: Transgenic tobacco plants overexpressing cotton glutathione S-transferase (GST) show enhanced resistance to methyl viologen. J Plant Physiol. 2003 Nov;160(11):1305-11. Six antioxidant enzymes, glutathione S-transferase, peroxidase (EC 1.11.1.9), superoxide dismutase (EC 1.15.1.1), peroxidase (EC 1.11.1.7), catalase (EC 1.11.1.6), and peroxidase (EC 1.11.1.11) were monitored in transgenic lines and non-transgenic control during MV treatments. |
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| 16936100 | Schlieve CR, Lieven CJ, Levin LA: Biochemical activity of reactive species scavengers do not predict retinal ganglion cell survival. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3878-86. Last, H2O2 induced intramitochondrial O2-, whereas paraquat produced O2- outside of the mitochondria, and these areas of generation can mislead interpretations of ROS scavenger activity and effectiveness. Scavengers tested were catalase, polyethylene glycol-superoxide dismutase (PEG-SOD), (III) tetrakis (1-methyl-4-pyridyl) (MnTMPyP), 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), deferoxamine, and U-74389G. |
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| 14732293 | O'Malley YQ, Reszka KJ, Britigan BE: Direct oxidation of 2',7'-dichlorodihydrofluorescein by pyocyanin and other redox-active compounds independent of reactive species production. Free Radic Biol Med. 2004 Jan 1;36(1):90-100. However, paraquat, plumbagin, streptonigrin, doxorubicin, daunorubicin, and 5-iminodaunorubicin did not. |
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| 11762696 | Si ML, Al-Sharafi B, Lai CC, Khardori R, Chang C, Su CY: Gender difference in cytoprotection induced by on female and male bovine aortic endothelial cells. Endocrine. 2001 Aug;15(3):255-62. Bovine aortic endothelial cells from both genders were preconditioned for 24 h with E2 (1 nM to 10 microM), and their resistance to paraquat (1 mM, 3 h), a generator, was measured using an MTT assay. |
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| 15487314 | Okamoto Y, Aoki S, Mataga I: Enhancement of amphotericin B activity against Candida albicans by Mycopathologia. 2004 Jul;158(1):9-15. This study aimed to examine the involvement of oxidative damage in amphotericin B (AmB) activity against Candida albicans using the (O2-) generator paraquat (PQ). |
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| 18620719 | Black AT, Gray JP, Shakarjian MP, Laskin DL, Heck DE, Laskin JD: Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):384-92. Epub 2008 May 29. Paraquat treatment also resulted in increased expression of HO-1, Cu,Zn-SOD, catalase, GSTP1, GSTA3 and GSTA4. |
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| 15077630 | Ananieva EA, Christov KN, Popova LP: Exogenous treatment with leads to increased antioxidant capacity in leaves of barley plants exposed to paraquat. J Plant Physiol. 2004 Mar;161(3):319-28. To further define the role of SA in paraquat induced responses, we analysed the capacity of the antioxidative defence system by measuring the activities of several antioxidative enzymes: superoxide dismutase (SOD, EC 1.15.1.1), peroxidase (APX, EC 1.11.1.11), glutathione reductase (GR, EC 1.6.4.2), reductase (DHAR, EC 1.8.5.1), catalase (CAT, EC 1.11.1.6), and peroxidase (POX, EC 1.11.1.7). |
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| 19709234 | Mannisto MK, Puhakka JA: Psychrotolerant and microaerophilic bacteria in boreal groundwater. FEMS Microbiol Ecol. 2002 Jul 1;41(1):9-16. In semisolid and PYGV media, 59% and 28% of the isolates, respectively, preferred microaerophilic growth and 33% were catalase-negative. The microaerophilic isolates had the highest sensitivity to H (2) O (2) whereas sensitivity to the generator paraquat was similar among microaerophilic and aerobic isolates. |
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| 18269170 | Spiegelman BM: Transcriptional control of energy homeostasis through the PGC1 coactivators. Novartis Found Symp. 2007;286:3-6; discusssion 6-12 This includes genes encoding mitochondrial proteins like SOD2, but also includes cytoplasmic proteins like catalase and GPX1. Cells lacking PGC1alpha are hypersensitive to death from oxidative stress caused by H2O2 or paraquat. |
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| 10924225 | Malarczyk E, Pazdzioch-Czochra M: Multiple respiratory bursts as a response to veratrate stress in Rhodococcus erythropolis cells. Cell Biol Int. 2000;24(8):515-27. The oxidase activity, measured as uptake against in the membrane pellets of MAX and MIN stage cells, differed in their response to the exogenous presence of FAD, ATP, cAMP, catalase, GSH, H (2) O (2) and methoxyphenolic substrates. |
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| 17640563 | Samai M, Sharpe MA, Gard PR, Chatterjee PK: Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity. Free Radic Biol Med. 2007 Aug 15;43(4):528-34. Epub 2007 May 16. The data presented here suggest that SODm such as EUK-134 and tempol, which possess additional catalase and/or ROS-scavenging activities, can significantly reduce renal cell damage caused by paraquat. |
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| 16984741 | Saffi J, Sonego L, Varela QD, Salvador M: Antioxidant activity of in wild-type and superoxide dismutase deficient strains of Saccharomyces cerevisiae. Redox Rep. 2006;11(4):179-84. These results demonstrate that due to the damage caused by paraquat, the antioxidant protection of seems to be mediated by catalase levels in yeast cells. |
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| 15465637 | Peixoto F, Vicente J, Madeira VM: A comparative study of plant and animal mitochondria exposed to paraquat reveals that peroxide is not related to the observed toxicity. Toxicol In Vitro. 2004 Dec;18(6):733-9. Paraquat (10 mM) inhibited all the enzymatic activities; excluding catalase all the other activities were inhibited to a similar degree. |
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| 17446436 | Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J: Sirt1 regulates aging and resistance to oxidative stress in the heart. . Circ Res. 2007 May 25;100(10):1512-21. Epub 2007 Apr 19. Moderate overexpression of Sirt1 protected the heart from oxidative stress induced by paraquat, with increased expression of antioxidants, such as catalase, through forkhead box O (FoxO)-dependent mechanisms, whereas high levels of Sirt1 increased oxidative stress in the heart at baseline. |
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| 19439226 | Page MM, Salmon AB, Leiser SF, Robb EL, Brown MF, Miller RA, Stuart JA: Mechanisms of stress resistance in Snell dwarf mouse fibroblasts: enhanced antioxidant and DNA base excision repair capacity, but no differences in mitochondrial metabolism. Free Radic Biol Med. 2009 Apr 15;46(8):1109-18. Epub 2009 Jan 23. Dwarf mouse cells deprived of serum and challenged with exposure to paraquat or peroxide showed a generally greater upregulation of catalase and DNA base excision repair enzymes. |
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| 15941311 | Wilmsen PK, Spada DS, Salvador M: Antioxidant activity of the in chemical and biological systems. J Agric Food Chem. 2005 Jun 15;53(12):4757-61. Paraquat induced higher catalase and superoxide dismutase than did peroxide, which only increased catalase activity. |
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| 11250117 | Mockett RJ, Orr WC, Rahmandar JJ, Sohal BH, Sohal RS: Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster. Exp Gerontol. 2001 Mar;36(3):441-63. In fact, catalase activity was significantly lower in the long-lived flies. Long life was largely maintained under heat stress and starvation conditions, and was maintained to a lesser extent upon exposure to paraquat, a generator. |
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| 11165630 | Schwanz P, Polle A: Growth under elevated CO (2) ameliorates defenses against photo-oxidative stress in poplar (Populus alba x tremula). Environ Exp Bot. 2001 Feb;45(1):43-53. To test the hypothesis that growth-CO (2) concentrations affect stress susceptibility, leaves of poplar trees (Populus alba x tremula) grown under ambient or about twofold ambient CO (2) concentrations were subjected to chilling temperatures at high light intensities or were exposed to paraquat. and -related detoxification systems as well as catalase (EC 1.11.1.6) activities were less resistant than superoxide dismutases and declined in stress-exposed leaves from poplars grown under elevated [CO (2)] to a similar extent as in those from trees grown under ambient [CO (2)]. |
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| 19043665 | Ding S, Lu Q, Zhang Y, Yang Z, Wen X, Zhang L, Lu C: Enhanced sensitivity to oxidative stress in transgenic tobacco plants with decreased glutathione reductase activity leads to a decrease in pool and redox state. Plant Mol Biol. 2009 Mar;69(5):577-92. Epub 2008 Nov 29. MV treatment induced an increase in the activities of GR, peroxidase, superoxide dismutase, and catalase. |
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| 11448761 | Orendi G, Zimmermann P, Baar C, Zentgraf U: Loss of stress-induced expression of catalase3 during leaf senescence in Arabidopsis thaliana is restricted to oxidative stress. Plant Sci. 2001 Jul;161(2):301-314. Different stress conditions can induce changes in the activity of the antioxidant enzymes superoxide dismutase (SOD, EC 1.15.1.1), peroxidase (APX, EC 1.11.1.11) and catalase (CAT, EC 1.11.1.6). The enzyme activities of all SOD and APX isoforms detected in young Arabidopsis leaves remained unaffected or slightly decreased after moderate paraquat treatment. |
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