Protein Information

Name CB 2
Synonyms CB 2; CNR2; CB2; CNR 2; CX5; Cannabinoid receptor 2; cannabinoid receptor 2 (macrophage); Cannabinoid receptor 2s…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
18538428 Jimenez-Del-Rio M, Daza-Restrepo A, Velez-Pardo C: The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. Neurosci Res. 2008 Aug;61(4):404-11. Epub 2008 May 2.

In this study, we demonstrate for the first time that CP55,940, a nonselective CB (1)/CB (2) cannabinoid receptor agonist, significantly protects and rescues Drosophila melanogaster against paraquat (PQ) toxicity via a receptor-independent mechanism.
81(1,1,1,1) Details