Protein Information

Name p65
Synonyms Erythrocyte 65 kDa protein; p65

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
16919916 Mitra S, Abraham E: Participation of superoxide in neutrophil activation and cytokine production. Biochim Biophys Acta. 2006 Aug;1762(8):732-41. Epub 2006 Jul 8.

Exposure of neutrophils to paraquat also enhanced phosphorylation of Ser536 in the p65 subunit of NF-kappaB an event associated with increased transcriptional activity.
81(1,1,1,1) Details
19567158 Shang Y, Xu SP, Wu Y, Jiang YX, Wu ZY, Yuan SY, Yao SL: Melatonin reduces acute lung injury in endotoxemic rats. Chin Med J. 2009 Jun 20;122(12):1388-93.

The pulmonary expression of nuclear factor-kappa B (NF-kappaB) p65 was evaluated by Western blotting.
BACKGROUND: Treatment with melatonin significantly reduces lung injury induced by bleomycin, paraquat and ischemia reperfusion.
2(0,0,0,2) Details
11728812 Zhou LZ, Johnson AP, Rando TA: NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells. Free Radic Biol Med. 2001 Dec 1;31(11):1405-16.


The NF kappa B complexes included a p50/p65 heterodimer, a p50 homodimer, and a p50/RelB heterodimer.
1(0,0,0,1) Details