Protein Information

Name protein kinase B
Synonyms AKT; PKB; Protein kinase B; AKT 1; AKT1; C AKT; Oncogene AKT1; PKB alpha…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
10539768 Cheng WH, Valentine BA, Lei XG: High levels of dietary vitamin E do not replace cellular glutathione peroxidase in protecting mice from acute oxidative stress. J Nutr. 1999 Nov;129(11):1951-7.

In Experiment 1, mice were fed torula yeast-based, Se-adequate (0.4 mg/kg as sodium selenite) diets + 0, 75, 750 or 7,500 mg all-rac-alpha-tocopheryl acetate for 5 wk before an intraperitoneal injection of 50 mg paraquat/kg body weight.
7(0,0,1,2) Details
16687388 Niso-Santano M, Moran JM, Garcia-Rubio L, Gomez-Martin A, Gonzalez-Polo RA, Soler G, Fuentes JM: Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death. Toxicol Sci. 2006 Aug;92(2):507-15. Epub 2006 May 9.
112(1,2,2,2) Details
11292860 Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD: Regulation of longevity and stress resistance by Sch9 in yeast. Science. 2001 Apr 13;292(5515):288-90. Epub 2001 Apr 5.


The protein kinase Akt/protein kinase B (PKB) is implicated in insulin signaling in mammals and functions in a pathway that regulates longevity and stress resistance in Caenorhabditis elegans.
1(0,0,0,1) Details