| Name | c Myc |
|---|---|
| Synonyms | MYC; Myc proto oncogene protein; Oncogene MYC; Transcription factor p64; c Myc; v myc avian myelocytomatosis viral oncogene homolog; v myc myelocytomatosis viral oncogene homolog (avian); Myc proto oncogene proteins… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12654481 | Cheng WH, Quimby FW, Lei XG: Impacts of glutathione peroxidase-1 knockout on the protection by injected against the pro-oxidant-induced liver aponecrosis and signaling in -deficient mice. Free Radic Biol Med. 2003 Apr 1;34(7):918-27. The paraquat-mediated gene or protein expression of proapoptotic Bax, Bcl-w, and Bcl-X (S), cell survival/death factors GADD45, MDM2, c-Myc, and caspase-3 was upregulated, but that of antiapoptotic Bcl-2 was downregulated in the GPX1-/- mice vs. the WT mice. |
81(1,1,1,1) | Details |
| 16182431 | Chen CM, Chou HC, Hsu HH, Wang LF: Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis. Toxicology. 2005 Dec 15;216(2-3):181-7. Epub 2005 Sep 22. Increases in TGF-beta1 mRNA expression and TGF-beta1 levels preceded the onset of increased collagen I mRNA expression and contents. c-myc mRNA expressions were inversely correlated with TGF-beta1 protein levels in paraquat-treated lungs. |
6(0,0,1,1) | Details |
| 12934716 | Paul A, Duttaroy A: Genomic regions responsible for manganese superoxide dismutase regulation in Drosophila melanogaster. Aging Cell. 2003 Aug;2(4):223-31. The transcription of manganese superoxide dismutase (MnSOD), expression of which is essential for detoxification of radicals from mitochondria, has been shown to be regulated in vitro by many factors and conditions including oxidative stress, cytokines, lipopolysaccharide, cytoplasmic myc (c-myc), p53 and tumour necrosis factors. Changes in MnSOD expression were positively associated with paraquat sensitivity of the deletion genotypes. |
1(0,0,0,1) | Details |