| Name | RNase |
|---|---|
| Synonyms | HP RNase; Ribonuclease; Ribonuclease A; Pancreatic ribonuclease; Pancreatic ribonuclease precursor; RIB 1; RIB1; RNASE1… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10759888 | Nanbu-Wakao R, Asoh S, Nishimaki K, Tanaka R, Ohta S: Bacterial cell death induced by human pro-apoptotic Bax is blocked by an RNase E mutant that functions in an anti-oxidant pathway. Genes Cells. 2000 Mar;5(3):155-67. CONCLUSIONS: The N-terminal region of the RNase E protein inhibits bacterial death induced by human Bax as well as paraquat through a unique mechanism that is distinct from RNA digestion. |
39(0,1,2,4) | Details |
| 10986244 | Gifford CM, Blaisdell JO, Wallace SS: Multiprobe RNase protection assay analysis of mRNA levels for the Escherichia coli oxidative DNA glycosylase genes under conditions of oxidative stress. J Bacteriol. 2000 Oct;182(19):5416-24. None of the genes were induced by peroxide, paraquat, X rays, or conditions that induce the SOS response. |
2(0,0,0,2) | Details |
| 19219992 | Wu J, Jiang Z, Liu M, Gong X, Wu S, Burns CM, Li Z: Polynucleotide phosphorylase protects Escherichia coli against oxidative stress. Biochemistry. 2009 Mar 10;48(9):2012-20. Further, when challenged with H (2) O (2), PNPase-deficient cells accumulate 8-oxoG in cellular RNA to a greater extent than wild-type cells, suggesting that this RNase functions in minimizing oxidized RNA in vivo. |
1(0,0,0,1) | Details |
| 11502194 | Hayakawa H, Kuwano M, Sekiguchi M: Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein. Biochemistry. 2001 Aug 21;40(33):9977-82. The RNase protection assay and gel shift assay revealed that some proteins bind specifically to 8-oxoguanine-containing RNA, hence preventing nuclease attacks. This protein was identified as polynucleotide phosphorylase, encoded by the pnp gene. pnp (-)() mutants are hyperresistant to paraquat, a drug that induces oxidative stress in the cell. |
1(0,0,0,1) | Details |