Protein Information

Name interleukin 1 beta
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
17535659 Jian XD, Sui H, Chu ZH, Zhang ZW, Kan BT, Zhang L, Zhang HT: [Changes of serum cytokine caused by acute paraquat poisoning] . Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007 Apr;25(4):230-2.

OBJECTIVE: To observe the change of cytokine interleukin IL-1 beta, IL-6, IL-10, tumor necrosis factor-alpha (TNF-alpha) occurred in acute paraquat (PQ) poisoning rats and to investigate the mechanism of acute lung injury caused by paraquat (PQ) poisoning.
32(0,1,1,2) Details
12935482 Tomita M, Okuyama T, Hidaka K: Changes in mRNAs of inducible nitric oxide synthase and interleukin-1 beta in the liver, kidney and lung tissues of rats acutely exposed to paraquat. Leg Med. 1999 Sep;1(3):127-34.
8(0,0,1,3) Details
20095326 Huang M, Zhang P, Chang XL, Gu XA, Wu Q, Zhou ZJ: [Changes of cytokine and nuclear factor-kappa B in acute paraquat poisoned rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Aug;27(8):463-7.

On the 1st, the 3rd, the 7th, the 14th, the 28th and the 56th day after treatment, the level of interleukin-1 beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha), transforming growth factor-beta 1 (TGF-beta1) and platelet-derived growth factor (PDGF) in serum were detected; the activity of NF-kappaB in lung tissues was detected.
4(0,0,0,4) Details
19505674 Santana MC, Garcia CS, Xisto DG, Nagato LK, Lassance RM, Prota LF, Ornellas FM, Capelozzi VL, Morales MM, Zin WA, Pelosi P, Rocco PR: Prone position prevents regional alveolar hyperinflation and mechanical stress and strain in mild experimental acute lung injury. Respir Physiol Neurobiol. 2009 Jun 30;167(2):181-8. Epub 2009 Apr 14.

In experimental mild acute lung injury (ALI), arterial oxygen partial pressure (Pa O2), lung mechanics and histology, inflammatory markers [interleukin (IL)-6 and IL-1 beta], and type III procollagen (PCIII) mRNA expressions were analysed in supine and prone position.
In controls, saline was intraperitoneally injected while ALI was induced by paraquat.
1(0,0,0,1) Details
10490279 Tampo Y, Tsukamoto M, Yonaha M: Superoxide production from paraquat evoked by exogenous NADPH in pulmonary endothelial cells. Free Radic Biol Med. 1999 Sep;27(5-6):588-95.

Under these conditions, superoxide production was enhanced with agonists, including interleukin-1beta, A23187, and phorbol 12-myristate 13-acetate.
1(0,0,0,1) Details
11264896 Tomita M, Okuyama T, Ishikawa T, Hidaka K, Nohno T: The role of nitric oxide in paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line. Free Radic Res. 2001 Feb;34(2):193-202.

0(0,0,0,0) Details