Protein Information

Name GSTA4
Synonyms GST class alpha; GST class alpha member 4; GSTA 4; GSTA4; GSTA4 protein; GSTA4 4; GTA 4; GTA4…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
16510128 Patel S, Singh V, Kumar A, Gupta YK, Singh MP: Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration. Brain Res. 2006 Apr 7;1081(1):9-18. Epub 2006 Feb 28.

The present study was therefore undertaken to investigate the mechanism of maneb- and paraquat-induced neurodegeneration by estimating the level of antioxidant defense enzymes in the striatum and measuring the differential expressions of CYP2E1 and GSTA4-4 genes.
39(0,1,2,4) Details
18620719 Black AT, Gray JP, Shakarjian MP, Laskin DL, Heck DE, Laskin JD: Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):384-92. Epub 2008 May 29.

Paraquat treatment also resulted in increased expression of HO-1, Cu,Zn-SOD, catalase, GSTP1, GSTA3 and GSTA4.
6(0,0,1,1) Details