| Name | xanthine oxidase |
|---|---|
| Synonyms | XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase… |
| Name | copper sulfate |
|---|---|
| CAS | sulfuric acid copper(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2820500 | Huber KR, Sridhar R, Griffith EH, Amma EL, Roberts J: Superoxide dismutase-like activities of (II) complexes tested in serum. Biochim Biophys Acta. 1987 Sep 24;915(2):267-76. The electron paramagnetic resonance technique of spin trapping was used to detect the formation of (O2-.) and other free radicals in the -xanthine oxidase system under a variety of conditions. |
4(0,0,0,4) | Details |
| 1554379 | Pelletier O, Hill I, Birnboim HC: Inhibition by superoxide dismutase-mimetic complexes of phorbol ester-induced respiratory burst in human granulocytes. Biochem Pharmacol. 1992 Mar 3;43(5):1061-6. Two superoxide dismutase-mimetic lipophilic complexes, Cu (II) 2 (indomethacin) 4 [Cu (II) 2 (indo) 4] and Cu (II) 2 (3,5-diisopropylsalicylate) 4 [Cu (II) 2 (3,5-DIPS) 4], were tested for their effects on the respiratory burst of intact human granulocytes and on xanthine oxidase, under conditions where and peroxide were generated. Similar inhibitory effects were seen using copper sulfate. |
2(0,0,0,2) | Details |
| 8485631 | Berman RS, Martin W: Arterial endothelial barrier dysfunction: actions of and the -xanthine oxidase free radical generating system. Br J Pharmacol. 1993 Apr;108(4):920-6. |
2(0,0,0,2) | Details |
| 9166989 | Napoli C, Triggiani M, Palumbo G, Condorelli M, Chiariello M, Ambrosio G: Glycosylation enhances radical-induced modifications and decreases acetylhydrolase activity of human low density lipoprotein. Basic Res Cardiol. 1997 Apr;92(2):96-105. METHODS: In vitro glc-LDL and n-LDL were exposed to the oxidants /xanthine oxidase (X/XO; 2 mM and 100 mU/ml, respectively), or CuSO4 (10 microM) for 18 hs at 37 degrees C. |
1(0,0,0,1) | Details |
| 9808343 | Hayashi A, Ryu A, Suzuki T, Kawada A, Tajima S: In vitro degradation of tropoelastin by reactive species. Arch Dermatol Res. 1998 Sep;290(9):497-500. Treatment of tropoelastin with copper sulfate/ resulted in degradation of tropoelastin producing fragments of molecular weight 45, 30 and 10 kDa within 30 min. ROS induced by the /xanthine oxidase system also degraded tropoelastin within 6 h. |
1(0,0,0,1) | Details |
| 8005513 | Sandstrom BE, Granstrom M, Marklund SL: New roles for quin2: powerful transition-metal ion chelator that inhibits -, but potentiates iron-driven, Fenton-type reactions. Free Radic Biol Med. 1994 Feb;16(2):177-85. Chelation of ferric ion with quin2 uniformly strongly enhanced the formation of oxidizing species, detected with the DMSO and assays, both by H2O2 and a mixture of / peroxide produced by /xanthine oxidase. |
1(0,0,0,1) | Details |
| 2540067 | Simpson JA, Smith SE, Dean RT: Scavenging by alginate of free radicals released by macrophages. . Free Radic Biol Med. 1989;6(4):347-53. In agreement with this, alginate was also able to scavenge radicals generated by a chemical system peroxide and detected by hydroxylation and chemiluminescence), and by an enzymatic system and xanthine oxidase; detected by chemiluminescence). |
1(0,0,0,1) | Details |