Protein Information

Name IleRS
Synonyms IARS 2; IleRS; Isoleucine tRNA ligase; IARS2; Mitochondrial isoleucine tRNA synthetase; Mitochondrial isoleucine tRNA synthetases

Compound Information

Name pelargonic acid
CAS nonanoic acid

Reference List

PubMed Abstract RScore(About this table)
11584022 Nakama T, Nureki O, Yokoyama S: Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. J Biol Chem. 2001 Dec 14;276(50):47387-93. Epub 2001 Oct 2.


We determined the crystal structures of the IleRS from the thermophilic eubacterium, Thermus thermophilus, in complexes with Ile-AMS and mupirocin at 3.0- and 2.5-A resolutions, respectively.
2(0,0,0,2) Details