| Name | G protein coupled receptors |
|---|---|
| Synonyms | ASRT 2; ASRT2; G protein coupled receptor 154; G protein coupled receptor for asthma susceptibility; G protein coupled receptor; G protein coupled receptor PGR14; GPR154; GPRA… |
| Name | abscisic acid |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19513236 | Chen JG: Heterotrimeric G-protein signaling in Arabidopsis: Puzzling G-protein-coupled receptor. Plant Signal Behav. 2008 Dec;3(12):1042-5. In Arabidopsis thaliana, GCR2 has been proposed as a GPCR for the plant hormone abscisic acid. |
2(0,0,0,2) | Details |
| 17347412 | Liu X, Yue Y, Li B, Nie Y, Li W, Wu WH, Ma L: A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid. Science. 2007 Mar 23;315(5819):1712-6. Epub 2007 Mar 8. Here, we report that a G protein-coupled receptor genetically and physically interacts with the G protein alpha subunit GPA1 to mediate all known ABA responses in Arabidopsis. |
2(0,0,0,2) | Details |
| 16263907 | Hsieh MH, Goodman HM: A novel gene family in Arabidopsis encoding putative heptahelical transmembrane proteins homologous to human adiponectin receptors and receptors. J Exp Bot. 2005 Dec;56(422):3137-47. Epub 2005 Nov 1. A novel seven-transmembrane receptor family, that is comprised of human adiponectin receptors (AdipoRs) and membrane receptors (mPRs) that share little sequence homology with all known G protein-coupled receptors (GPCRs), has been identified recently. Steady-state levels of HHP1 mRNA are increased by treatments with abscisic acid and whereas levels of HHP2 mRNA are increased by abscisic acid and benzyladenine treatments. |
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| 17894782 | Gao Y, Zeng Q, Guo J, Cheng J, Ellis BE, Chen JG: Genetic characterization reveals no role for the reported ABA receptor, GCR2, in ABA control of seed germination and early seedling development in Arabidopsis. Plant J. 2007 Dec;52(6):1001-13. Epub 2007 Sep 25. Abscisic acid (ABA) is perceived by several different types of receptors in plant cells. GCR2 was also proposed to be a seven-transmembrane (7TM) G-protein-coupled receptor (GPCR). |
1(0,0,0,1) | Details |
| 18086512 | Illingworth CJ, Parkes KE, Snell CR, Mullineaux PM, Reynolds CA: Criteria for confirming sequence periodicity identified by Fourier transform analysis: application to GCR2, a candidate plant GPCR?. Biophys Chem. 2008 Mar;133(1-3):28-35. Epub 2007 Nov 22. The method has been applied to G-protein coupled receptor (GPCR) sequences, by Fourier transformation of hydrophobicity values, codon frequencies and the extent of over-representation of codon pairs; the latter being related to translational step times. GCR2 has recently been proposed as the plant GPCR receptor for the hormone abscisic acid. |
1(0,0,0,1) | Details |
| 17629540 | Hirayama T, Shinozaki K: Perception and transduction of abscisic acid signals: keys to the function of the versatile plant hormone ABA. Trends Plant Sci. 2007 Aug;12(8):343-51. Epub 2007 Jul 12. Recent breakthroughs identifying FCA, which is an RNA-binding protein, the Mg-chelatase H subunit, and a G protein-coupled receptor as receptors for ABA provide a major leap forward in understanding the initial steps of ABA signaling mechanisms. |
1(0,0,0,1) | Details |
| 20015036 | Bassaganya-Riera J, Skoneczka J, Kingston DG, Krishnan A, Misyak SA, Guri AJ, Pereira A, Carter AB, Minorsky P, Tumarkin R, Hontecillas R: Mechanisms of action and medicinal applications of abscisic Acid. . Curr Med Chem. 2010;17(5):467-78. A few ABA molecular targets have been identified in vitro (e.g., signaling, G protein-coupled receptors) in both plant and animal systems. |
1(0,0,0,1) | Details |
| 15155892 | Pandey S, Assmann SM: The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. Plant Cell. 2004 Jun;16(6):1616-32. Epub 2004 May 21. Heterotrimeric G proteins composed of alpha, beta, and gamma subunits link ligand perception by G protein-coupled receptors (GPCRs) with downstream effectors, providing a ubiquitous signaling mechanism in eukaryotes. |
1(0,0,0,1) | Details |
| 16581874 | Pandey S, Chen JG, Jones AM, Assmann SM: G-protein complex mutants are hypersensitive to abscisic acid regulation of germination and postgermination development. Plant Physiol. 2006 May;141(1):243-56. Epub 2006 Mar 31. To assess new roles for the Arabidopsis (Arabidopsis thaliana) Galpha subunit (GPA1), the Gbeta subunit (AGB1), and the candidate G-protein-coupled receptor (GCR1) in ABA signaling during germination and early seedling development, we utilized knockout mutants lacking one or more of these components. |
1(0,0,0,1) | Details |
| 17322342 | Warpeha KM, Upadhyay S, Yeh J, Adamiak J, Hawkins SI, Lapik YR, Anderson MB, Kaufman LS: The GCR1, GPA1, PRN1, NF-Y signal chain mediates both blue light and abscisic acid responses in Arabidopsis. Plant Physiol. 2007 Apr;143(4):1590-600. Epub 2007 Feb 23. The chain consists of GCR1 (the sole Arabidopsis protein coding for a potential G-protein-coupled receptor), GPA1 (the sole Arabidopsis Galpha-subunit), Pirin1 (PRN1; one of four members of an iron-containing subgroup of the cupin superfamily), and a nuclear factor Y heterotrimer comprised of A5, B9, and possibly C9. |
1(0,0,0,1) | Details |
| 16415218 | Warpeha KM, Lateef SS, Lapik Y, Anderson M, Lee BS, Kaufman LS: G-protein-coupled receptor 1, G-protein Galpha-subunit 1, and prephenate dehydratase 1 are required for blue light-induced production of in etiolated Arabidopsis. Plant Physiol. 2006 Mar;140(3):844-55. Epub 2006 Jan 13. Insertion mutagenesis confirms that GPA1 and the sole canonical G-protein-coupled receptor (GCR1) in Arabidopsis also have a role in this blue light-mediated event. Data are also presented to confirm that abscisic acid can act through the same pathway. |
1(0,0,0,1) | Details |
| 17991845 | Johnston CA, Temple BR, Chen JG, Gao Y, Moriyama EN, Jones AM, Siderovski DP, Willard FS: Comment on "A G protein coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid". Science. 2007 Nov 9;318(5852):914; author reply 914. |
87(1,1,2,2) | Details |
| 19826234 | Tuteja N: Signaling through G protein coupled receptors. . Plant Signal Behav. 2009 Oct;4(10):942-7. Epub 2009 Oct 14. |
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