Protein Information

Name LEC1
Synonyms CIRL 2; Latrophilin 1; CIRL2; CL2; Calcium independent alpha latrotoxin receptor 2; LEC 1; LEC1; LPHH 1…

Compound Information

Name abscisic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
18689444 Mu J, Tan H, Zheng Q, Fu F, Liang Y, Zhang J, Yang X, Wang T, Chong K, Wang XJ, Zuo J: LEAFY COTYLEDON1 is a key regulator of fatty acid biosynthesis in Arabidopsis. Plant Physiol. 2008 Oct;148(2):1042-54. Epub 2008 Aug 8.

Genetic analysis indicates that the LEC1 function is partially dependent on ABSCISIC ACID INSENSITIVE3, FUSCA3, and WRINKLED1 in the regulation of fatty acid biosynthesis.
85(1,1,1,5) Details
15695450 Kagaya Y, Toyoshima R, Okuda R, Usui H, Yamamoto A, Hattori T: LEAFY COTYLEDON1 controls seed storage protein genes through its regulation of FUSCA3 and ABSCISIC ACID INSENSITIVE3. Plant Cell Physiol. 2005 Mar;46(3):399-406. Epub 2005 Feb 2.

Arabidopsis ABSCISIC ACID INSENSEITIVE3 (ABI3), FUSCA3 (FUS3) and LEAFY COTYLEDON1 (LEC1) encode key transcription factors that control seed maturation events, including seed storage protein (SSP) accumulation.
12(0,0,1,7) Details
17158584 Suzuki M, Wang HH, McCarty DR: Repression of the LEAFY COTYLEDON 1/B3 regulatory network in plant embryo development by VP1/ABSCISIC ACID INSENSITIVE 3-LIKE B3 genes. Plant Physiol. 2007 Feb;143(2):902-11. Epub 2006 Dec 8.

Plant embryo development is regulated by a network of transcription factors that include LEAFY COTYLEDON 1 (LEC1), LEC1-LIKE (L1L), and B3 domain factors, LEAFY COTYLEDON 2 (LEC2), FUSCA3 (FUS3), and ABSCISIC ACID INSENSITIVE 3 (ABI3) of Arabidopsis (Arabidopsis thaliana).
9(0,0,1,4) Details
19207209 Yamamoto A, Kagaya Y, Toyoshima R, Kagaya M, Takeda S, Hattori T: Arabidopsis NF-YB subunits LEC1 and LEC1-LIKE activate transcription by interacting with seed-specific ABRE-binding factors. Plant J. 2009 Jun;58(5):843-56. Epub 2009 Feb 3.

8(0,0,0,8) Details
16731585 To A, Valon C, Savino G, Guilleminot J, Devic M, Giraudat J, Parcy F: A network of local and redundant gene regulation governs Arabidopsis seed maturation. Plant Cell. 2006 Jul;18(7):1642-51. Epub 2006 May 26.

In Arabidopsis thaliana, four major regulators (ABSCISIC ACID INSENSITIVE3 [ABI3], FUSCA3 [FUS3], LEAFY COTYLEDON1 [LEC1], and LEC2) control most aspects of seed maturation, such as accumulation of storage compounds, cotyledon identity, acquisition of desiccation tolerance, and dormancy.
7(0,0,1,2) Details
18024558 Tanaka M, Kikuchi A, Kamada H: The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination. Plant Physiol. 2008 Jan;146(1):149-61. Epub 2007 Nov 16.

In Arabidopsis (Arabidopsis thaliana), the transcription factors LEAFY COTYLEDON1 (LEC1), FUSCA3 (FUS3), and ABSCISIC ACID INSENSITIVE3 (ABI3) play key roles in embryogenesis.
7(0,0,1,2) Details
17384168 Malik MR, Wang F, Dirpaul JM, Zhou N, Polowick PL, Ferrie AM, Krochko JE: Transcript profiling and identification of molecular markers for early microspore embryogenesis in Brassica napus. Plant Physiol. 2007 May;144(1):134-54. Epub 2007 Mar 23.

Sequencing results suggest that embryogenesis is clearly established in a subset of the microspores by 7 d of culture and that this time point is optimal for isolation of embryo-specific expressed sequence tags such as ABSCISIC ACID INSENSITIVE3, ATS1, LEC1, LEC2, and FUSCA3.
7(0,0,1,2) Details
18476867 Santos-Mendoza M, Dubreucq B, Baud S, Parcy F, Caboche M, Lepiniec L: Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis. Plant J. 2008 May;54(4):608-20.

In the model plant Arabidopsis, genetic analyses have demonstrated that LEAFY COTYLEDON genes, namely LEC1, LEC2 and FUSCA3 (FUS3), are key transcriptional regulators of seed maturation, together with ABSCISIC ACID INSENSITIVE 3 (ABI3).
7(0,0,1,2) Details
18552352 Malik MR, Wang F, Dirpaul JM, Zhou N, Hammerlindl J, Keller W, Abrams SR, Ferrie AM, Krochko JE: Isolation of an embryogenic line from non-embryogenic Brassica napus cv. J Exp Bot. 2008;59(10):2857-73. Epub 2008 Jun 13.

Expression analysis of marker genes for embryogenesis in Westar and the derived DH-2 line, using real-time reverse transcription-PCR, revealed that the timely expression of embryogenesis-related genes such as LEAFY COTYLEDON1 (LEC1), LEC2, ABSCISIC ACID INSENSITIVE3, and BABY BOOM1, and an accompanying down-regulation of pollen-related transcripts, were associated with commitment to embryo development in Brassica microspores.
6(0,0,1,1) Details
19893533 Yin P, Fan H, Hao Q, Yuan X, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N: Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec;16(12):1230-6. Epub 2009 Nov 5.

In response to ABA binding, loop CL2 closes onto the pocket, creating a surface that recognizes ABI1.
2(0,0,0,2) Details
16935993 Casson SA, Lindsey K: The turnip mutant of Arabidopsis reveals that LEAFY COTYLEDON1 expression mediates the effects of auxin and sugars to promote embryonic cell identity. Plant Physiol. 2006 Oct;142(2):526-41. Epub 2006 Aug 25.

Mapping and molecular characterization of tnp shows that it represents a gain-of-function mutant of LEAFY COTYLEDON1 (LEC1), due to a promoter mutation.
Penetrance of the mutant phenotype is strongly enhanced in the presence of exogenous auxin and sugars, but not by gibberellin or abscisic acid, and is antagonized by cytokinin.
2(0,0,0,2) Details
19754639 Sugliani M, Rajjou L, Clerkx EJ, Koornneef M, Soppe WJ: Natural modifiers of seed longevity in the Arabidopsis mutants abscisic acid insensitive3-5 (abi3-5) and leafy cotyledon1-3 (lec1-3). New Phytol. 2009 Dec;184(4):898-908. Epub 2009 Sep 14.

The Shahdara modifiers can partially re-establish the seed developmental programs controlled by LEC1 and restore the accumulation of seed storage proteins that are reduced in abi3-5 and lec1-3. *The isolation and characterization of natural modifiers of the seed maturation mutants abi3-5 and lec1-3, and the analysis of their seed proteomes, advance our current understanding of seed longevity.
1(0,0,0,1) Details
18203869 Suzuki M, Latshaw S, Sato Y, Settles AM, Koch KE, Hannah LC, Kojima M, Sakakibara H, McCarty DR: The Maize Viviparous8 locus, encoding a putative ALTERED MERISTEM PROGRAM1-like peptidase, regulates abscisic acid accumulation and coordinates embryo and endosperm development. Plant Physiol. 2008 Mar;146(3):1193-206. Epub 2008 Jan 18.

Consistent with the early-onset viviparous phenotype of vp8, expression of several embryonic regulators, including LEC1/B3 domain transcription factors, was reduced in the mutant embryo.
1(0,0,0,1) Details