Protein Information

Name PP2C phosphatase
Synonyms Ca(2+)/calmodulin dependent protein kinase phosphatase; CaM kinase phosphatase; CaMKPase; FEM 2; FEM2; POPX 2; POPX2; PP2C phosphatase…

Compound Information

Name abscisic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
19407143 Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A, Grill E: Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science. 2009 May 22;324(5930):1064-8. Epub 2009 Apr 30.
81(1,1,1,1) Details
19659659 Guerriero G, Martin N, Golovko A, Sundstrom JF, Rask L, Ezcurra I: The RY/Sph element mediates transcriptional repression of maturation genes from late maturation to early seedling growth. New Phytol. 2009 Nov;184(3):552-65. Epub 2009 Jul 29.

Using transgenic and transient approaches in Nicotiana, we examined activities of two ABI3-dependent reporter genes driven by multimeric RY and abscisic acid response elements (ABREs) from a Brassica napus napin gene, termed RY and ABRE, where the RY reporter requires ABI3 DNA binding.
The ABI3 transactivation of RY is inhibited by staurosporine, by a PP2C phosphatase, and by a repressor of maturation genes, VAL1/HSI2.
1(0,0,0,1) Details
19955427 Lee SC, Lan W, Buchanan BB, Luan S: A protein kinase-phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21419-24. Epub 2009 Dec 2.

The plant hormone abscisic acid (ABA) serves as a physiological monitor to assess the water status of plants and, under drought conditions, induces stomatal pore closure by activating specific ion channels, such as a slow-anion channel (SLAC1) that, in turn, mediate ion efflux from the guard cells.
PP2CA, one of the PP2C phosphatase family members acts in an opposing manner and inhibits the activity of SLAC1 by two mechanisms: (1) direct interaction with SLAC1 itself, and (2) physical interaction with OSTI leading to inhibition of the kinase independently of phosphatase activity.
1(0,0,0,1) Details
20192755 Cutler SR, Rodriguez PL, Finkelstein RR, Abrams SR: Abscisic Acid: Emergence of a Core Signaling Network. Annu Rev Plant Biol. 2010 Feb 8.

0(0,0,0,0) Details