Protein Information

Name phospholipase D (protein family or complex)
Synonyms Phospholipase D

Compound Information

Name abscisic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
15197253 Zhang W, Qin C, Zhao J, Wang X: Phospholipase D alpha 1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9508-13. Epub 2004 Jun 14.
82(1,1,1,2) Details
16099207 Zhang W, Yu L, Zhang Y, Wang X: Phospholipase D in the signaling networks of plant response to abscisic acid and reactive oxygen species. Biochim Biophys Acta. 2005 Sep 5;1736(1):1-9.
7(0,0,1,2) Details
16877031 Bargmann BO, Munnik T: The role of phospholipase D in plant stress responses. Curr Opin Plant Biol. 2006 Oct;9(5):515-22. Epub 2006 Jul 31.

2(0,0,0,2) Details
18573189 Racagni G, Villasuso AL, Pasquare SJ, Giusto NM, Machado E: Diacylglycerol pyrophosphate inhibits the alpha-amylase secretion stimulated by gibberellic acid in barley aleurone. Physiol Plant. 2008 Nov;134(3):381-93. Epub 2008 Jun 19.


In this study, we show that PA produced by phospholipase D (E.C. 3.1.4.4) during the antagonist effect of ABA in GA signaling is rapidly phosphorylated by phosphatidate kinase (PAK) to DGPP.
1(0,0,0,1) Details
17876344 Li G, Lin F, Xue HW: Genome-wide analysis of the phospholipase D family in Oryza sativa and functional characterization of PLD beta 1 in seed germination. Cell Res. 2007 Oct;17(10):881-94.

2(0,0,0,2) Details
17261695 Mane SP, Vasquez-Robinet C, Sioson AA, Heath LS, Grene R: Early PLDalpha-mediated events in response to progressive drought stress in Arabidopsis: a transcriptome analysis. J Exp Bot. 2007;58(2):241-52.

Phospholipase D (PLD) has been implicated in a variety of stresses including osmotic stress and wounding.
PLDalpha1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and promotes abscisic acid signalling.
1(0,0,0,1) Details
15807778 Zalejski C, Zhang Z, Quettier AL, Maldiney R, Bonnet M, Brault M, Demandre C, Miginiac E, Rona JP, Sotta B, Jeannette E: Diacylglycerol pyrophosphate is a second messenger of abscisic acid signaling in Arabidopsis thaliana suspension cells. Plant J. 2005 Apr;42(2):145-52.

In a previous study, we demonstrated that the stimulation of phospholipase D (PLD) activity and plasma membrane anion currents by ABA were both required for RAB18 expression in Arabidopsis thaliana suspension cells.
1(0,0,0,1) Details
18364466 Hong Y, Pan X, Welti R, Wang X: Phospholipase Dalpha3 is involved in the hyperosmotic response in Arabidopsis. Plant Cell. 2008 Mar;20(3):803-16. Epub 2008 Mar 25.

Rapid activation of phospholipase D (PLD), which hydrolyzes membrane lipids to generate phosphatidic acid (PA), occurs under various hyperosmotic conditions, including salinity and water deficiency.
PLDalpha3-KO plants display increased sensitivities to salinity and water deficiency and also tend to induce abscisic acid-responsive genes more readily than wild-type plants, whereas PLDalpha3-OE plants have decreased sensitivities.
1(0,0,0,1) Details
19704505 Hong Y, Pan X, Welti R, Wang X: The effect of phospholipase Dalpha3 on Arabidopsis response to hyperosmotic stress and glucose. Plant Signal Behav. 2008 Dec;3(12):1099-100.

Phospholipase D (PLD) hydrolyzes membrane lipids to produce the messenger phosphatidic acid (PA), and the activation of PLD occurs under different hyperosmotic stresses, including dehydration and salt stress.
The involvement of PLDalpha3 in hyperosmotic stress is through a different mechanism from that PLDalpha1, which mediates the effect of abscisic acid on stomatal movements.
1(0,0,0,1) Details
16333570 Motes CM, Pechter P, Yoo CM, Wang YS, Chapman KD, Blancaflor EB: Differential effects of two phospholipase D inhibitors, 1-butanol and N-acylethanolamine, on in vivo cytoskeletal organization and Arabidopsis seedling growth. Protoplasma. 2005 Dec;226(3-4):109-23. Epub 2005 Dec 12.

In plants, NAEs have been shown to inhibit phospholipase Dalpha (PLDalpha) activity, interfere with abscisic acid-induced stomatal closure, and retard Arabidopsis seedling development. 1-Butanol, an antagonist of PLD-dependent phosphatidic acid production, was reported to induce defects in Arabidopsis seedling development that were somewhat similar to effects induced by elevated levels of NAE.
1(0,0,0,1) Details
18179780 Liu PF, Chang WC, Wang YK, Chang HY, Pan RL: Signaling pathways mediating the suppression of Arabidopsis thaliana Ku gene expression by abscisic acid. Biochim Biophys Acta. 2008 Mar;1779(3):164-74. Epub 2007 Dec 15.

Moreover, analysis of inhibitor treatments and ABA-responsive mutants suggested that AtKu repression by ABA was mediated through the pathway of extracellular Ca (2+), phospholipase D alpha, p38-type mitogen-activated protein kinase (MAPK), MAPK6 and ABA transcription factors, ABI3 and ABI5.
1(0,0,0,1) Details
15504732 Zou X, Seemann JR, Neuman D, Shen QJ: A WRKY gene from creosote bush encodes an activator of the abscisic acid signaling pathway. J Biol Chem. 2004 Dec 31;279(53):55770-9. Epub 2004 Oct 25.

0(0,0,0,0) Details
15202712 Kolla VA, Suhita D, Raghavendra AS: Marked changes in volume of mesophyll protoplasts of pea (Pisum sativum) on exposure to growth hormones. J Plant Physiol. 2004 May;161(5):557-62.


Four plant hormones: gibberellic acid (GA3), indole 3-acetic acid (IAA), abscisic acid (ABA)(+/-) and methyl jasmonate (MJ), caused marked changes in the volume of mesophyll protoplasts.
0(0,0,0,0) Details