| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | abscisic acid |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15882944 | Kitahata N, Saito S, Miyazawa Y, Umezawa T, Shimada Y, Min YK, Mizutani M, Hirai N, Shinozaki K, Yoshida S, Asami T: Chemical regulation of abscisic acid catabolism in plants by cytochrome P450 inhibitors. Bioorg Med Chem. 2005 Jul 15;13(14):4491-8. Abscisic acid (ABA) catabolism in plants is primarily regulated by ABA 8'-hydroxylase, which is a cytochrome P450 (P450). |
112(1,2,2,2) | Details |
| 15604685 | Narusaka Y, Narusaka M, Seki M, Umezawa T, Ishida J, Nakajima M, Enju A, Shinozaki K: Crosstalk in the responses to abiotic and biotic stresses in Arabidopsis: analysis of gene expression in cytochrome P450 gene superfamily by cDNA microarray. Plant Mol Biol. 2004 May;55(3):327-42. In this study, expression patterns of these cytochrome P450 genes were analyzed by a full-length cDNA microarray under various treatments, such as hormones jasmonic acid, ethylene, abscisic acid), pathogen-inoculation ( Alternaria brassicicola , Alternaria alternata ), paraquat, rose bengal, UV stress (UV-C), heavy metal stress (CuSO4), mechanical wounding, drought, high salinity and low temperature. |
10(0,0,1,5) | Details |
| 16696948 | Kim YC, Kim SY, Paek KH, Choi D, Park JM: Suppression of CaCYP1, a novel cytochrome P450 gene, compromises the basal pathogen defense response of pepper plants. Biochem Biophys Res Commun. 2006 Jun 30;345(2):638-45. Epub 2006 May 2. Our results indicated that CaCYP1, a novel cytochrome P450 in pepper plants, may play a role in plant defense response pathways that involve and abscisic acid signaling pathways. |
9(0,0,1,4) | Details |
| 19513806 | Cheng WH, Chiang MH, Hwang SG, Lin PC: Antagonism between abscisic acid and ethylene in Arabidopsis acts in parallel with the reciprocal regulation of their metabolism and signaling pathways. Plant Mol Biol. 2009 Sep;71(1-2):61-80. Epub 2009 Jun 10. Moreover, by microarray analysis we found that an ACC oxidase (ACO) was significantly upregulated in the aba2 mutant, whereas the 9-CIS-EPOXYCAROTENOID DIOXYGENASE 3 (NCED3) gene in ein2 was upregulated, and both the ABSCISIC ACID INSENSITIVE1 (ABI1) and cytochrome P450, family 707, subfamily A, polypeptide 2 (CYP707A2) genes in etr1-1 were downregulated. |
6(0,0,1,1) | Details |
| 17073787 | Hamberger B, Bohlmann J: Cytochrome P450 mono-oxygenases in conifer genomes: discovery of members of the terpenoid oxygenase superfamily in spruce and pine. Biochem Soc Trans. 2006 Dec;34(Pt 6):1209-14. While most terpenoids are characterized as specialized or secondary metabolites, some terpenoids, such as the phytohormones GA BRs (brassinosteroids) and ABA (abscisic acid), have essential functions in plant growth and development. |
2(0,0,0,2) | Details |
| 15064374 | Saito S, Hirai N, Matsumoto C, Ohigashi H, Ohta D, Sakata K, Mizutani M: Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid. Plant Physiol. 2004 Apr;134(4):1439-49. Epub 2004 Apr 2. The hydroxylation at the 8'-position of ABA is known as the key step of ABA catabolism, and this reaction is catalyzed by ABA 8'-hydroxylase, a cytochrome P450. |
1(0,0,0,1) | Details |
| 15240257 | Siewers V, Smedsgaard J, Tudzynski P: The P450 monooxygenase BcABA1 is essential for abscisic acid biosynthesis in Botrytis cinerea. Appl Environ Microbiol. 2004 Jul;70(7):3868-76. Targeted inactivation of the gene bccpr1 encoding a cytochrome P450 oxidoreductase reduced the ABA production significantly, proving the involvement of P450 monooxygenases in the pathway. |
1(0,0,0,1) | Details |
| 15012200 | Rademacher W: GROWTH RETARDANTS: Effects on Biosynthesis and Other Metabolic Pathways. Annu Rev Plant Physiol Plant Mol Biol. 2000 Jun;51:501-531. These retardants block cytochrome P450-dependent monooxygenases, thereby inhibiting oxidation of ent-kaurene into ent-kaurenoic acid. (c) Structural mimics of which is the co-substrate of dioxygenases that catalyze late steps of GA formation. Enzymes, similar to the ones involved in GA biosynthesis, are also of importance in the formation of abscisic acid, ethylene, sterols, flavonoids, and other plant constituents. |
1(0,0,0,1) | Details |
| 18196465 | Chakrabarti M, Bowen SW, Coleman NP, Meekins KM, Dewey RE, Siminszky B: CYP82E4-mediated to conversion in tobacco is regulated by a senescence-specific signaling pathway. Plant Mol Biol. 2008 Mar;66(4):415-27. Epub 2008 Jan 15. In plants that carry the high trait, conversion is primarily catalyzed by a cytochrome P450 protein, designated CYP82E4 whose transcription is strongly upregulated during leaf senescence. Treatments of leaf tissue with various signaling molecules including abscisic acid, ethylene, jasmonic acid, and yeast extract; and stresses, such as drought, wounding and tobacco mosaic virus infection did not enhance conversion or GUS activity in the green leaves, but an increase in CYP82E4 expression was observed in response to ethylene- or tobacco mosaic virus-induced senescence. |
1(0,0,0,1) | Details |
| 16332414 | Kim YJ, Kim DG, Lee SH, Lee I: Wound-induced expression of the 5-hydroxylase gene in Camptotheca acuminata. Biochim Biophys Acta. 2006 Feb;1760(2):182-90. Epub 2005 Nov 10. 5-hydroxylase (F5H) is a cytochrome P450-dependent monooxygenase that catalyses the hydroxylation of coniferaldehyde and coniferyl leading to sinapic acid and syringyl lignin biosynthesis. |
1(0,0,0,1) | Details |
| 15044947 | Kushiro T, Okamoto M, Nakabayashi K, Yamagishi K, Kitamura S, Asami T, Hirai N, Koshiba T, Kamiya Y, Nambara E: The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism. EMBO J. 2004 Apr 7;23(7):1647-56. Epub 2004 Mar 25. The hormonal action of abscisic acid (ABA) in plants is controlled by the precise balance between its biosynthesis and catabolism. |
1(0,0,0,1) | Details |
| 15310824 | Tallman G: Are diurnal patterns of stomatal movement the result of alternating metabolism of endogenous guard cell ABA and accumulation of ABA delivered to the apoplast around guard cells by transpiration?. J Exp Bot. 2004 Sep;55(405):1963-76. Epub 2004 Aug 13. Abscisic acid (ABA) prevents opening of closed stomata and causes open stomata to close. At first light, xanthophyll cycling, isomerization of ABA precursors, and activation of a cytochrome P450 mono-oxygenase (CytP450) would deplete endogenous guard cell ABA. |
1(0,0,0,1) | Details |
| 16623881 | Umezawa T, Okamoto M, Kushiro T, Nambara E, Oono Y, Seki M, Kobayashi M, Koshiba T, Kamiya Y, Shinozaki K: CYP707A3, a major ABA 8'-hydroxylase involved in dehydration and rehydration response in Arabidopsis thaliana. Plant J. 2006 Apr;46(2):171-82. Abscisic acid (ABA) catabolism is one of the determinants of endogenous ABA levels affecting numerous aspects of plant growth and abiotic stress responses. The major ABA catabolic pathway is triggered by ABA 8'-hydroxylation catalysed by the cytochrome P450 CYP707A family. |
1(0,0,0,1) | Details |
| 20008451 | Morant M, Ekstrom C, Ulvskov P, Kristensen C, Rudemo M, Olsen CE, Hansen J, Jorgensen K, Jorgensen B, Moller BL, Bak S: Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2. Mol Plant. 2010 Jan;3(1):192-211. Epub 2009 Dec 14. Subsequently, SUR2 was identified as CYP83B1, a cytochrome P450 positioned at the metabolic branch point between auxin and glucosinolate metabolism. The complex phenotype of sur2 may thus not only be assigned to elevated levels of auxin, but also to ethylene and abscisic acid responses as well as drought responses in the absence of a water deficiency. |
1(0,0,0,1) | Details |
| 18036199 | Galbiati M, Simoni L, Pavesi G, Cominelli E, Francia P, Vavasseur A, Nelson T, Bevan M, Tonelli C: Gene trap lines identify Arabidopsis genes expressed in stomatal guard cells. Plant J. 2008 Mar;53(5):750-62. Epub 2007 Nov 23. The screen yielded two insertions in annotated genes, encoding the CYTOCHROME P450 86A2 (CYP86A2) mono-oxygenase, and the PLEIOTROPIC DRUG RESISTANCE 3 (AtPDR3) transporter. Examination of homozygous mutant lines revealed that abscisic acid (ABA)-induced stomatal closure was impaired in the atpdr3 mutant. |
1(0,0,0,1) | Details |