Protein Information

Name xanthine dehydrogenase
Synonyms XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase…

Compound Information

Name abscisic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
16784786 Mendel RR, Bittner F: Cell biology of molybdenum. . Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.

In eukaryotes, the most prominent Mo-enzymes are (1) sulfite oxidase, which catalyzes the final step in the degradation of sulfur-containing amino acids and is involved in detoxifying excess sulfite, (2) xanthine dehydrogenase, which is involved in purine catabolism and reactive oxygen production, (3) aldehyde oxidase, which oxidizes a variety of aldehydes and is essential for the biosynthesis of the phytohormone abscisic acid, and in autotrophic organisms also (4) nitrate reductase, which catalyzes the key step in inorganic nitrogen assimilation.
31(0,1,1,1) Details
15941399 Yesbergenova Z, Yang G, Oron E, Soffer D, Fluhr R, Sagi M: The plant Mo-hydroxylases aldehyde oxidase and xanthine dehydrogenase have distinct reactive oxygen species signatures and are induced by drought and abscisic acid. Plant J. 2005 Jun;42(6):862-76.
7(0,0,1,2) Details
16033776 Kaiser BN, Gridley KL, Ngaire Brady J, Phillips T, Tyerman SD: The role of molybdenum in agricultural plant production. . Ann Bot. 2005 Oct;96(5):745-54. Epub 2005 Jul 20.

Enzymes that require molybdenum for activity include nitrate reductase, xanthine dehydrogenase, aldehyde oxidase and sulfite oxidase.
SCOPE: Loss of Mo-dependent enzyme activity (directly or indirectly through low internal molybdenum levels) impacts upon plant development, in particular, those processes involving nitrogen metabolism and the synthesis of the phytohormones abscisic acid and indole-3 butyric acid.
1(0,0,0,1) Details
16669776 Schwarz G, Mendel RR: Molybdenum cofactor biosynthesis and molybdenum enzymes. Annu Rev Plant Biol. 2006;57:623-47.

There are four Mo enzymes in plants: (1) nitrate reductase catalyzes the first and rate-limiting step in nitrate assimilation and is structurally similar to the recently identified, (2) peroxisomal sulfite oxidase that detoxifies excessive sulfite. (3) Aldehyde oxidase catalyzes the last step of abscisic acid biosynthesis, and (4) xanthine dehydrogenase is essential for purine degradation and stress response.
There are four Mo enzymes in plants: (1) nitrate reductase catalyzes the first and rate-limiting step in nitrate assimilation and is structurally similar to the recently identified, (2) peroxisomal sulfite oxidase that detoxifies excessive sulfite. (3) Aldehyde oxidase catalyzes the last step of abscisic acid biosynthesis, and (4) xanthine dehydrogenase is essential for purine degradation and stress response.
1(0,0,0,1) Details