| Name | brain derived neurotrophic factor |
|---|---|
| Synonyms | Abrineurin; BDNF; Brain derived neurotrophic factor; Brain derived neurotrophic factor precursor; Neurotrophin; Brain derived neurotrophic factors; Brain derived neurotrophic factor precursors; Neurotrophins |
| Name | permethrin |
|---|---|
| CAS | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12111003 | Imamura L, Hasegawa H, Kurashina K, Matsuno T, Tsuda M: Neonatal exposure of newborn mice to pyrethroid (permethrin) represses activity-dependent c-fos mRNA expression in cerebellum. Arch Toxicol. 2002 Jul;76(7):392-7. Epub 2002 May 29. In a previous report, we demonstrated that the exposure of cultured mouse cerebellar granule cells to permethrin, a type I pyrethroid insecticide, repressed the induction of activity-dependent c- fos and brain-derived neurotrophic factor (BDNF) gene expression, accompanying a decrease in Ca (2+) influx into neurons. |
43(0,1,3,3) | Details |
| 11082455 | Imamura L, Hasegawa H, Kurashina K, Hamanishi A, Tabuchi A, Tsuda M: Repression of activity-dependent c-fos and brain-derived neurotrophic factor mRNA expression by pyrethroid insecticides accompanying a decrease in Ca (2+) influx into neurons. J Pharmacol Exp Ther. 2000 Dec;295(3):1175-82. The membrane depolarization induced by elevating the (K (+)) concentration in medium (high K (+)) caused the activation of c-fos and BDNF genes, which was also repressed by permethrin. |
34(0,1,1,4) | Details |
| 15527870 | Imamura L, Kurashina K, Kawahira T, Omoteno M, Tsuda M: Additional repression of activity-dependent c-fos and BDNF mRNA expression by lipophilic compounds accompanying a decrease in Ca2+ influx into neurons. Neurotoxicology. 2005 Jan;26(1):17-25. In our previous study, we reported that permethrin and some other pyrethroid insecticides, which are suspected of being EDs, repressed the induction of c-fos and BDNF mRNA expression, accompanying a reduction of Ca2+ influx at doses non-toxic to CGCs. |
32(0,1,1,2) | Details |