| PubMed |
Abstract |
RScore(About this table) |
| 16387282 |
Ross MK, Borazjani A, Edwards CC, Potter PM: Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases. Biochem Pharmacol. 2006 Feb 28;71(5):657-69. Epub 2006 Jan 4.
Pure human CEs (hCE-1 and hCE-2), a rabbit CE (rCE), and two rat CEs (Hydrolases A and B) were used to study the hydrolytic metabolism of the following pyrethroids: 1Rtrans-resmethrin (bioresmethrin), 1RStrans-permethrin, and 1RScis-permethrin. hCE-1 and hCE-2 hydrolyzed trans-permethrin 8- and 28-fold more efficiently than cis-permethrin (when k (cat)/K (m) values were compared), respectively. |
63(0,2,2,3) |
Details |
| 18983829 |
Yang D, Pearce RE, Wang X, Gaedigk R, Wan YJ, Yan B: Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. Biochem Pharmacol. 2009 Jan 15;77(2):238-47. Epub 2008 Oct 15.
|
8(0,0,1,3) |
Details |
| 16359636 |
Nishi K, Huang H, Kamita SG, Kim IH, Morisseau C, Hammock BD: Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Arch Biochem Biophys. 2006 Jan 1;445(1):115-23.
For example, the trans-isomers of permethrin and cypermethrin were hydrolyzed much faster than corresponding cis-counterparts by both enzymes. |
4(0,0,0,4) |
Details |