Name | ATPase |
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Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
Name | permethrin |
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CAS | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
PubMed | Abstract | RScore(About this table) | |
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12615099 | Kakko I, Toimela T, Tahti H: The synaptosomal membrane bound ATPase as a target for the effects of pyrethroids, permethrin and cypermethrin. Chemosphere. 2003 May;51(6):475-80. |
281(3,4,5,6) | Details |
6284178 | Ghiasuddin SM, Kawauchi S, Matsumura F, Doherty JD: Role of phospholipids in the inhibitory action of DDT and permethrin on the nerve ATPase of lobster, Homarus americanus. Biochem Pharmacol. 1982 Apr 15;31(8):1483-9. ATPase inhibition by DDT and permethrin was found to be highest in preparations where the phospholipids were removed by the above treatments, next highest with the untreated original enzyme, and least with the reconstituted ATPase regardless of the source of phospholipids used for reconstitution. |
197(2,3,3,7) | Details |
15652757 | Grosman N, Diel F: Influence of pyrethroids and piperonyl butoxide on the Ca (2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. Int Immunopharmacol. 2005 Feb;5(2):263-70. At the highest concentration tested, permethrin (10 microM) alone inhibited the ATPase activity of leukocyte membranes by 20%, whereas the synaptosomes were affected less. |
115(1,2,2,5) | Details |
2957417 | Sahib IK, Prasada Rao KS, Desaiah D: Pyrethroid inhibition of basal and calmodulin stimulated Ca2+ ATPase and adenylate cyclase in rat brain. J Appl Toxicol. 1987 Apr;7(2):75-80. None of the pyrethroids inhibited synaptosomal basal Ca2+ ATPase, but permethrin and deltamethrin inhibited basal adenylate cyclase in the nuclear fraction of a brain homogenate. |
40(0,1,2,5) | Details |
8258384 | Kodavanti PR, Mundy WR, Tilson HA, Harry GJ: Effects of selected neuroactive chemicals on cerebellum and on survival of cerebellar granule cells. Fundam Appl Toxicol. 1993 Oct;21(3):308-16. Ca2+ extrusion, measured as Ca (2+)-ATPase activity, was determined in synaptosomes prepared by density gradient. However, chlorpromazine (CPZ), aluminum (Al), permethrin (PER), and deltamethrin (DEL) inhibited Ca2+ sequestration by mitochondria and microsomes. |
transporting systems in rat 3(0,0,0,3) | Details |
9106117 | Rao GV, Rao KS: Modulation of K+ transport across synaptosomes of rat brain by synthetic pyrethroids. J Neurol Sci. 1997 Apr 15;147(2):127-33. transport across synaptosomes was studied under the influence of two synthetic pyrethroids, (Permethrin, without the cyano group) and Cypermethrin (CPM, with the cyano group). K+ transport is regulated by Na (+)-K (+)-ATPase, K (+)-ATPase and K+ channels. |
2(0,0,0,2) | Details |