| Name | calcineurin (protein family or complex) |
|---|---|
| Synonyms | Calcineurin; Calcineurins; Protein phosphatase 2B |
| Name | permethrin |
|---|---|
| CAS | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9714322 | Fakata KL, Swanson SA, Vorce RL, Stemmer PM: Pyrethroid insecticides as phosphatase inhibitors. . Biochem Pharmacol. 1998 Jun 15;55(12):2017-22. The type II pyrethroid insecticides cis-cypermethrin (c-Cyp), trans-cypermethrin, deltamethrin (Delt), and fenvalerate A alpha (Fen), as well as the type I pyrethroid insecticides cis- and trans-permethrin and S-bioallethrin, were unable to inhibit the phosphatase activity of purified calcineurin under conditions of maximal activation by Ca2+ and calmodulin. |
82(1,1,1,2) | Details |
| 10535451 | Poulsen CR, Bokvist K, Olsen HL, Hoy M, Capito K, Gilon P, Gromada J: Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells. Diabetes. 1999 Nov;48(11):2171-81. Inhibition of exocytosis by ATP resulted from G-protein-dependent activation of the serine/threonine protein phosphatase calcineurin and was abolished by cyclosporin A and deltamethrin. |
1(0,0,0,1) | Details |
| 12837755 | Hoy M, Berggren PO, Gromada J: Involvement of protein kinase C-epsilon in inositol hexakisphosphate-induced exocytosis in mouse pancreatic beta-cells. J Biol Chem. 2003 Sep 12;278(37):35168-71. Epub 2003 Jul 1. In the presence of inhibitors of the protein phosphatase calcineurin to block endocytosis, intracellular application of InsP6 produced a dose-dependent stimulation of exocytosis, and half-maximal effect was observed at 22 microM. |
1(0,0,0,1) | Details |