| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | phorate |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15294458 | Henderson MC, Krueger SK, Siddens LK, Stevens JF, Williams DE: S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2. Biochem Pharmacol. 2004 Sep 1;68(5):959-67. As the sulfoxide of phorate is a markedly less effective acetylcholinesterase inhibitor than the cytochrome P450 metabolites (oxon, oxon sulfoxide or oxon sulfone), humans possessing the FMO2*1 allele may be more resistant to organophosphate-mediated toxicity when pulmonary metabolism is an important route of exposure or disposition. |
31(0,1,1,1) | Details |
| 9323438 | Vandana S, Zzaman S: Phorate-induced enzymological alterations in mouse olfactory bulb. . Brain Res Bull. 1997;44(3):247-52. After 32 weeks of exposure animals were sacrificed and cryosections were processed for acetylcholinesterase and butyrylcholinesterase (AChE and BChE, respectively) enzyme localization. |
2(0,0,0,2) | Details |
| 6658844 | Singh DK, Agarwal RA: Inhibition kinetics of certain organophosphorus and pesticides on acetylcholinesterase from the snail Lymnaea acuminata. Toxicol Lett. 1983 Dec;19(3):313-9. k2, Kd and ki, for 2 organophosphorus (Phorate and Formothion) and 2 pesticides (Mexacarbate and Carbaryl) using acetylcholinesterase present in homogenates of the nervous tissue of the snail Lymnaea acuminata, were determined. |
8(0,0,1,3) | Details |
| 5153770 | Coppage DL: Characterization of fish brain acetylcholinesterase with an automated pH stat for inhibition studies. Bull Environ Contam Toxicol. 1971 Jul-Aug;6(4):304-10. |
1(0,0,0,1) | Details |
| 9619645 | Singh G, Mahajan R, Whig J: The importance of electrodiagnostic studies in acute organophosphate poisoning. J Neurol Sci. 1998 May 7;157(2):191-200. Electrodiagnostic studies revealed single stimulus induced repetitive responses and decrement-increment responses at 30 and 50 Hz repetitive nerve stimulation, findings that are indicative of a depolarization block due to inactivation of acetylcholinesterase at the motor end-plate. |
1(0,0,0,1) | Details |