| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | phosphine |
|---|---|
| CAS | phosphine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17600791 | Kasper PT, Back JW, Vitale M, Hartog AF, Roseboom W, de Koning LJ, van Maarseveen JH, Muijsers AO, de Koster CG, de Jong L: An aptly positioned azido group in the spacer of a protein cross-linker for facile mapping of lysines in close proximity. Chembiochem. 2007 Jul 23;8(11):1281-92. Two parallel reaction pathways are induced by tris (carboxyethyl) phosphine (TCEP) in cross-linked peptides from BAMG-treated cytochrome c. |
81(1,1,1,1) | Details |
| 17188248 | Caruso F, Villa R, Rossi M, Pettinari C, Paduano F, Pennati M, Daidone MG, Zaffaroni N: Mitochondria are primary targets in apoptosis induced by the mixed phosphine gold species chlorotriphenylphosphine-1,3-bis (diphenylphosphino) propanegold (I) in melanoma cell lines. Biochem Pharmacol. 2007 Mar 15;73(6):773-81. Epub 2006 Nov 28. Such an apoptotic response was mediated by a dose-dependent loss of mitochondrial membrane potential, cytochrome c and Smac/DIABLO release from mitochondria into cytosol and enhanced caspase-9 and caspase-3 catalytic activity. |
1(0,0,0,1) | Details |
| 17992291 | Scolaro C, Chaplin AB, Hartinger CG, Bergamo A, Cocchietto M, Keppler BK, Sava G, Dyson PJ: Tuning the hydrophobicity of ruthenium (II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy. Dalton Trans. 2007 Nov 21;(43):5065-72. Epub 2007 Sep 26. The antitumour activity of the organometallic ruthenium (ii)-arene mixed phosphine complexes, [Ru (eta (6)- Cl (PTA)(PPh (3))] BF (4) and [Ru (eta (6)-C (6) H (5) CH (2) CH (2) OH) Cl (PTA)(PPh (3))] BF (4) (PTA = 1,3,5-triaza-7-phosphaadamantane), have been evaluated in vitro and compared to their RAPTA analogues, [Ru (eta (6)- Cl (2)(PTA)] and [Ru (eta (6)-C (6) H (5) CH (2) CH (2) OH) Cl (2)(PTA)] . The decrease in selectivity has been correlated to increased DNA interactions relative to proteins, demonstrated by reactivity of the compounds with a 14-mer oligonucleotide and the model proteins ubiquitin and cytochrome-c. |
1(0,0,0,1) | Details |