Name | Ah receptor |
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Synonyms | AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs… |
Name | azobenzene |
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CAS | diphenyldiazene |
PubMed | Abstract | RScore(About this table) | |
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11995926 | Kato TA, Matsuda T, Matsui S, Mizutani T, Saeki K: Activation of the aryl hydrocarbon receptor by methyl yellow and related congeners: structure-activity relationships in halogenated derivatives. Biol Pharm Bull. 2002 Apr;25(4):466-71. In the study of compounds structurally related to MY, benzanilide (BA) showed almost the same AhR ligand activity as azobenzene and trans-stilbene. |
88(1,1,1,8) | Details |
8020164 | Cheung YL, Puddicombe SM, Gray TJ, Ioannides C: Mutagenicity and CYP1A induction by azobenzenes correlates with their carcinogenicity. Carcinogenesis. 1994 Jun;15(6):1257-63. In the presence of the Aroclor 1254-activation system, o-aminoazotoluene and 3-methoxy-4-aminoazobenzene were potent mutagens, whereas 4-amino-azobenzene and 4-diethylaminoazobenzene failed to elicit a positive mutagenic response. All six azobenzenes displaced [3H] tetrachlorodibenzo-p-dioxin from the cytosolic Ah receptor, with o-aminoazotoluene and 3-methoxy-4-aminoazobenzene being the most effective. |
1(0,0,0,1) | Details |