| Name | estrogen receptor |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | prochloraz |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15130599 | Hofmeister MV, Bonefeld-Jorgensen EC: Effects of the pesticides prochloraz and methiocarb on human estrogen receptor alpha and beta mRNA levels analyzed by on-line RT-PCR. Toxicol In Vitro. 2004 Aug;18(4):427-33. We have analyzed the effect of the currently used pesticides prochloraz and methiocarb on the estrogen receptor (ER) alpha and beta mRNA levels in parallel with the natural ligand, 17beta- (E2). |
56(0,1,5,6) | Details |
| 15261991 | Grunfeld HT, Bonefeld-Jorgensen EC: Effect of in vitro estrogenic pesticides on human oestrogen receptor alpha and beta mRNA levels. Toxicol Lett. 2004 Aug 1;151(3):467-80. After co-exposure with E2, all the tested pesticides counteracted the E2-induced decrease of the ERalpha mRNA level, but only significantly for prochloraz, dieldrin, and tolchlofos-methyl. |
11(0,0,1,6) | Details |
| 11884232 | Andersen HR, Vinggaard AM, Rasmussen TH, Gjermandsen IM, Bonefeld-Jorgensen EC: Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol. 2002 Feb 15;179(1):1-12. Twenty-four pesticides were tested for interactions with the estrogen receptor (ER) and the androgen receptor (AR) in transactivation assays. Pesticides (endosulfan, methiocarb, methomyl, pirimicarb, propamocarb, deltamethrin, fenpropathrin, dimethoate, chlorpyriphos, dichlorvos, tolchlofos-methyl, vinclozolin, iprodion, fenarimol, prochloraz, fosetyl-aluminum, chlorothalonil, daminozid, paclobutrazol, chlormequat chlorid, and ethephon) were selected according to their frequent use in Danish greenhouses. |
1(0,0,0,1) | Details |
| 15788727 | Vinggaard AM, Christiansen S, Laier P, Poulsen ME, Breinholt V, Jarfelt K, Jacobsen H, Dalgaard M, Nellemann C, Hass U: Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring. Toxicol Sci. 2005 Jun;85(2):886-97. Epub 2005 Mar 23. It antagonizes the androgen and the estrogen receptors, agonizes the Ah receptor, and inhibits aromatase activity. |
1(0,0,0,1) | Details |
| 16219411 | Bonefeld-Jorgensen EC, Grunfeld HT, Gjermandsen IM: Effect of pesticides on estrogen receptor transactivation in vitro: a comparison of stable transfected MVLN and transient transfected MCF-7 cells. Mol Cell Endocrinol. 2005 Dec 1;244(1-2):20-30. Epub 2005 Oct 10. The estrogenic potential of four pesticides (endosulfan, prochloraz, tolchlofos-methyl and propamocarb) was compared in parallel with 17beta- (E2) by reporter constructs in transient transfected MCF-7BUS and in stable transfected MVLN cells. |
1(0,0,0,1) | Details |
| 18800561 | Zhang X, Hecker M, Tompsett AR, Park JW, Jones PD, Newsted J, Au D, Kong R, Wu RS, Giesy JP: Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoconazole. Environ Sci Technol. 2008 Sep 1;42(17):6762-9. Fourteen-week-old Japanese medaka were exposed for seven days to concentrations of PCZ or KTC from 3.0 to 300 microg/L Exposure [corrected] to KTC or PCZ caused significant reduction of fecundity of Japanese medaka and down-regulated expression of estrogen receptor (ER)-alpha and egg precursors in livers of males and females. |
1(0,0,0,1) | Details |
| 10789375 | Vinggaard AM, Breinholt V, Larsen JC: Screening of selected pesticides for oestrogen receptor activation in vitro. Food Addit Contam. 1999 Dec;16(12):533-42. Several pesticides did not have any effect on the proliferation response after 6 days of exposure, including: chlorpyrifos, diuron, iprodion, linuron, pentachlorphenol, prochloraz, propioconazol, propyzamine, quintozen, tetrachorvinphos and tetradifon. |
0(0,0,0,0) | Details |