Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name demeton-S
CAS

Reference List

PubMed Abstract RScore(About this table)
7237776 Lewis PJ, Lowing RK, Gompertz D: Automated discrete kinetic method for erythrocyte acetylcholinesterase and plasma cholinesterase. Clin Chem. 1981 Jun;27(6):926-9.

To emphasize the need for measuring both erythrocyte acetylcholinesterase and plasma cholinesterase activity in workers exposed to organophosphate pesticides, we present a study of serial activities of both enzymes in a person accidentally exposed to demeton-S-methyl.
9(0,0,1,4) Details
15629114 Fischer S, Arad A, Margalit R: Lipsome-formulated enzymes for organophosphate scavenging: butyrylcholinesterase and Demeton-S. Arch Biochem Biophys. 2005 Feb 1;434(1):108-15.
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17582755 Luckarift HR, Greenwald R, Bergin MH, Spain JC, Johnson GR: Biosensor system for continuous monitoring of organophosphate aerosols. Biosens Bioelectron. 2007 Oct 31;23(3):400-6. Epub 2007 May 6.

The enzymes butyrylcholinesterase (BuChE) and organophosphate hydrolase (OPH) are stabilized by encapsulation in biomimetic silica nanoparticles, entrained within a packed bed column.
The system proved suitable for detection of a range of organophosphates including paraoxon, demeton-S and malathion.
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954759 Okonek S, Boelcke G, Hollmann H: Therapeutic properties.of haemodialysis and blood exchange transfusion in organophosphate poisoning. Eur J Intensive Care Med. 1976;2(1):13-8.

Human blood was contaminated with nitrostigmine, dimethoate and demeton-S-methyl sulfoxide.
The influence of blood exchange transfusion on poison elimination as well as on the cholinesterase activity of blood, brain and muscle was studied in rats poisoned with nitrostigmine.
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3993886 Kipling RM, Cruickshank AN: Organophosphate insecticide poisoning. Anaesthesia. 1985 Mar;40(3):281-4.


A case of acute poisoning with an organophosphate anticholinesterase insecticide is reported.
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