| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | azobenzene |
|---|---|
| CAS | diphenyldiazene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8687124 | Ohtaki Y, Hida T, Hiramatsu K, Kanitani M, Ohshima T, Nomura M, Wakita H, Aburada M, Miyamoto KI: as an endogenous risk factor for hepatocarcinogenesis and effects of gomisin A, a lignan component of Schizandra fruits. Anticancer Res. 1996 Mar-Apr;16(2):751-5. This study investigates the relationship between serum concentration of bile acids, the appearance of preneoplastic change, glutathione S-transferase placental form (GST-P)-positive foci in the liver of male Donryu rats which had been fed 0.06% 3'-methyl-4-dimethylamino-azobenzene (3'-MeDAB), and the effects of gomisin A, previously reported to inhibit the tumor promotion process. |
31(0,1,1,1) | Details |
| 8593453 | Miyamoto K, Hiramatsu K, Ohtaki Y, Kanitani M, Nomura M, Aburada M: Effects of gomisin A on the promotor action and serum bile acid concentration in hepatocarcinogenesis induced by 3'-methyl-4-dimethylamino-azobenzene. Biol Pharm Bull. 1995 Oct;18(10):1443-5. When different types of tumor promotors, phenobarbital (PB) and (DCA), were administered for 5 weeks after initiation by 3'-MeDAB, preneoplastic alterations in the liver, determined by glutathione S-transferase placental form (GST-P), were markedly increased. |
1(0,0,0,1) | Details |
| 8124661 | Nomura M, Nakachiyama M, Hida T, Ohtaki Y, Sudo K, Aizawa T, Aburada M, Miyamoto KI: Gomisin A, a lignan component of Schizandora fruits, inhibits development of preneoplastic lesions in rat liver by 3'-methyl-4-dimethylamino-azobenzene. Cancer Lett. 1994 Jan 15;76(1):11-8. Gomisin A inhibited both increases of the level of glutathione-S-transferase placental form (GST-P) and the number and size of GST-P positive foci in the liver increased after treatment with 3'-MeDAB. |
1(0,0,0,1) | Details |
| 12416023 | Karmakar R, Banik S, Chatterjee M: Inhibitory effect of on 3'methyl-4-dimethyl-amino-azobenzene-induced rat hepatocarcinogenesis: a study on antioxidant defense enzymes. J Exp Ther Oncol. 2002 Jul-Aug;2(4):193-9. Anticancer efficacy of VD3 was estimated using different possible biomarkers, namely (GSH) concentration, gamma-glutamyl transpeptidase (GGT) activity, glutathione S-transferase (GST) activity, glutathione reductase (GRd) activity, peroxidase (GPx) activity in hyperplastic nodules (HNs) and non-nodular surrounding parenchyma (NNSP) liver areas. |
1(0,0,0,1) | Details |