Protein Information

Name amine oxidase
Synonyms AOC 3; DAO; Diamine oxidase; Histaminase; Amine oxidase; AOC3; AOC3 Human placenta amine oxidase; Copper amine oxidase…

Compound Information

Name butylamine
CAS 2-butanamine

Reference List

PubMed Abstract RScore(About this table)
6779837 Floris G: [Salt effect on pig kidney diamine oxidase activity] . Boll Soc Ital Biol Sper. 1980 Aug 30;56(16):1638-42.

Different patterns were shown in the variation of enzymatic activity, according to the cationic species and the substrates tested (cadaverine and butylamine).
3(0,0,0,3) Details
2589850 De Boer L, Brouwer JW, Van Hassel CW, Levering PR, Dijkhuizen L: Nitrogen metabolism in the facultative methylotroph Arthrobacter P1 grown with various amines or ammonia as nitrogen sources. Antonie Van Leeuwenhoek. 1989 Oct;56(3):221-32.

The methylamine and formaldehyde produced were further metabolized via a primary amine oxidase and the ribulose monophosphate (RuMP) cycle.
Butylamine and benzylamine only functioned as nitrogen sources.
2(0,0,0,2) Details
10896215 Frebort I, Tanaka S, Matsushita K, Adachi O: Cellular localization and metabolic function of n-butylamine-induced amine oxidases in the fungus Aspergillus niger AKU 3302. Arch Microbiol. 2000 May-Jun;173(5-6):358-65.

It is proposed that the highly active amine oxidase AO-I is located in the cell wall and serves primarily as a detoxifying agent, preventing amines from entering and damaging the cell.
2(0,0,0,2) Details
2873143 Williamson PR, Kagan HM: Reaction pathway of bovine aortic lysyl oxidase. . J Biol Chem. 1986 Jul 15;261(20):9477-82.

Lineweaver-Burk plots revealed a pattern of parallel lines when the oxidation of n-butylamine was followed at different fixed concentrations of oxygen consistent with a "ping-pong" kinetic mechanism in which the aldehyde is produced and released before the binding of oxygen, the second substrate.
The kinetic mechanism of lysyl oxidase thus appears to be similar to those described for diamine oxidase and pig plasma monoamine oxidase.
1(0,0,0,1) Details
3813525 Middlehoven WJ, Hoogkamer-Te Niet MC, De Laat WT, Weijers C, Bulder CJ: Oxidation of amines by yeasts grown on 1-aminoalkanes or putrescine as the sole source of carbon, nitrogen and energy. Antonie Van Leeuwenhoek. 1986;52(6):525-35.


The maximum growth rate of Trichosporon cutaneum CBS 8111 in chemostat cultures was 0.185 h-1 on ethylamine and 0.21 h-1 on butylamine, that of Candida famata CBS 8109 was 0.32 h-1 on putrescine.
0(0,0,0,0) Details
9043630 Frebort I, Matsushita K, Adachi O: The fungus Gibberella fujikuroi produces copper/topaquinone-containing amine oxidase when induced by N-butylamine. Biochem Mol Biol Int. 1997 Jan;41(1):11-23.
12(0,0,2,2) Details
8166656 Stevanato R, Mondovi B, Befani O, Scarpa M, Rigo A: Electrostatic control of oxidative deamination catalysed by bovine serum amine oxidase. Biochem J. 1994 Apr 1;299 ( Pt 1):317-20.

The ionic-strength-dependence of steady-state kinetic parameters (kc and Km') for non-biogenic (benzylamine, butylamine) and biogenic (spermine, spermidine) amines has been measured in the bovine serum amine oxidase reaction.
7(0,0,1,2) Details
10052132 Frebort I, Matsushita K, Toyama H, Lemr K, Yamada M, Adachi O: Purification and characterization of methylamine oxidase induced in Aspergillus niger AKU 3302. Biosci Biotechnol Biochem. 1999 Jan;63(1):125-34.

Crude extract of Aspergillus niger AKU 3302 mycelia incubated with methylamine showed a single amine oxidase activity band in a developed polyacrylamide gel that weakly cross-reacted with the antibody against a copper/topa quinone-containing amine oxidase (AO-II) from the same strain induced by n-butylamine.
7(0,0,1,2) Details
1252460 Toraya T, Fujimura M, Ikeda SI, Fukui S, Yamada H: Affinity chromatography of amine oxidase from Aspergillus niger. Biochim Biophys Acta. 1976 Feb 20;420(2):316-22.

Although a small part of the enzyme was retained on the column through ionic interaction and eluted with 1.0 M potassium phosphate buffer (pH 7.2), most of the enzyme adsorbed was eluted with 0.5 M potassium phosphate buffer (pH 7.2) containing 10 mM butylamine.
3(0,0,0,3) Details