Protein Information

Name tumor necrosis factor alpha
Synonyms Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2…

Compound Information

Name cacodylic acid
CAS dimethylarsinic acid

Reference List

PubMed Abstract RScore(About this table)
9548797 Sakurai T, Kaise T, Matsubara C: Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms. Chem Res Toxicol. 1998 Apr;11(4):273-83.


The inorganic arsenicals also induced marked release of an inflammatory cytokine, tumor necrosis factor alpha (TNF alpha), at cytotoxic doses.
2(0,0,0,2) Details
11312651 Vega L, Styblo M, Patterson R, Cullen W, Wang C, Germolec D: Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes. Toxicol Appl Pharmacol. 2001 May 1;172(3):225-32.


Exposure to low doses of trivalent arsenicals stimulated secretion of the growth-promoting cytokines, granulocyte macrophage colony stimulating factor and tumor necrosis factor-alpha.
1(0,0,0,1) Details