| Name | MYP3 |
|---|---|
| Synonyms | MYP 3; MYP3 |
| Name | cacodylic acid |
|---|---|
| CAS | dimethylarsinic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18502017 | Nascimento MG, Suzuki S, Wei M, Tiwari A, Arnold LL, Lu X, Le XC, Cohen SM: Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro. Toxicology. 2008 Jul 10;249(1):69-74. Epub 2008 Apr 22. To determine if MYP3 cells metabolize arsenicals, cells were treated with arsenate, arsenite and MMA (V) as described above and the medium was analyzed by HPLC-ICPMS to determine species and quantity of arsenicals present. |
1(0,0,0,1) | Details |
| 19429254 | Suzuki S, Arnold LL, Pennington KL, Chen B, Le XC, Cohen SM: Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium. Toxicol Lett. 2009 Jun 1;187(2):124-9. Epub 2009 Mar 3. In this study, we investigated the growth effects of As (III) and an organic trivalent arsenical, dimethylarsinous acid (DMA (III)), and the effects of co-exposure of gefitinib, an EGFR inhibitor, with As (III) to a rat urothelial cell line (MYP3). |
1(0,0,0,1) | Details |
| 12230408 | Cohen SM, Arnold LL, Uzvolgyi E, Cano M, St John M, Yamamoto S, Lu X, Le XC: Possible role of dimethylarsinous acid in dimethylarsinic acid-induced urothelial toxicity and regeneration in the rat. Chem Res Toxicol. 2002 Sep;15(9):1150-7. Using rat (MYP3) and human (1T1) urothelial cells, cytotoxicity for trivalent arsenicals, arsenite, monomethylarsonous acid (MMA (III)), and DMA (III) was demonstrated at 0.4-4.8 microM concentrations, whereas MMA (V), DMA (V), and were cytotoxic at millimolar concentrations. |
1(0,0,0,1) | Details |