| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | cacodylic acid |
|---|---|
| CAS | dimethylarsinic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7843134 | Yamanaka K, Okada S: Induction of lung-specific DNA damage by metabolically methylated arsenics via the production of free radicals. Environ Health Perspect. 1994 Sep;102 Suppl 3:37-40. An in vitro experiment indicated that DNA single-strand breaks by dimethylarsine were suppressed by the presence of superoxide dismutase and catalase, suggesting that the strand breaks were induced via the production of free-radical species including active oxygens. |
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| 2017750 | Yamanaka K, Hasegawa A, Sawamura R, Okada S: Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice. Toxicol Appl Pharmacol. 1991 Apr;108(2):205-13. In male ICR mice given a single po dose (1500 mg/kg) of DMAA-Na, the activities of mitochondrial superoxide dismutase, peroxidase, and glucose-6-phosphate dehydrogenase significantly increased at 6 hr or longer after dosing, while cytosolic superoxide dismutase and catalase did not. |
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| 2484622 | Yamanaka K, Hasegawa A, Sawamura R, Okada S: DNA strand breaks in mammalian tissues induced by methylarsenics. Biol Trace Elem Res. 1989 Jul-Sep;21:413-7. Furthermore, the strand breaks after exposure to dimethylarsine were reduced in the presence of catalase and/or superoxide dismutase. |
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| 12971800 | Yoshida K, Kuroda K, Zhou X, Inoue Y, Date Y, Wanibuchi H, Fukushima S, Endo G: Urinary -containing metabolite produced by intestinal bacteria following oral administration of dimethylarsinic acid to rats. Chem Res Toxicol. 2003 Sep;16(9):1124-9. The cytotoxicity of in HL-60 cells was decreased by the addition of superoxide dismutase, suggesting that the cytotoxicity of might be due to the production of reactive species. |
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