| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | cacodylic acid |
|---|---|
| CAS | dimethylarsinic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12115560 | Nishikawa T, Wanibuchi H, Ogawa M, Kinoshita A, Morimura K, Hiroi T, Funae Y, Kishida H, Nakae D, Fukushima S: Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive species mechanism. Int J Cancer. 2002 Jul 10;100(2):136-9. Hepatic microsome cytochrome P-450 content was markedly increased with all 3 arsenic treatments. |
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| 19084030 | Medina-Diaz IM, Estrada-Muniz E, Reyes-Hernandez OD, Ramirez P, Vega L, Elizondo G: Arsenite and its metabolites, MMA (III) and DMA (III), modify CYP3A4, PXR and RXR alpha expression in the small intestine of CYP3A4 transgenic mice. Toxicol Appl Pharmacol. 2009 Sep 1;239(2):162-8. Epub 2008 Nov 24. Cytochrome P450 (P450) modification may be one of the factors contributing to these disorders. |
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| 9261921 | Brown JL, Kitchin KT, George M: Dimethylarsinic acid treatment alters six different rat biochemical parameters: relevance to arsenic carcinogenesis. Teratog Carcinog Mutagen. 1997;17(2):71-84. DNA damage (DD), cytochrome P450 content (P450), content (GSH), ODC, serum alanine aminotransferase (ALT) and HO were measured in liver and/or lung tissue. |
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