| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | chlorobenzilate |
|---|---|
| CAS | ethyl 4-chloro-α-(4-chlorophenyl)-α-hydroxybenzeneacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2387028 | Flodstrom S, Hemming H, Warngard L, Ahlborg UG: Promotion of altered hepatic foci development in rat liver, cytochrome P450 enzyme induction and inhibition of cell-cell communication by DDT and some structurally related organohalogen pesticides. Carcinogenesis. 1990 Aug;11(8):1413-7. The organochlorine pesticide 1,1'-(2,2,2-trichloroethylidene) bis (4-chlorobenzene) (DDT) and four structural analogues (bromopropylate, chlorobenzilate, dicofol and fenarimol) were investigated for their ability to inhibit gap junctional intercellular communication both in the Chinese hamster V79 metabolic co-operation assay and in the scrape-loading/dye-transfer assay in WB-F344 rat liver epithelial cells. |
1(0,0,0,1) | Details |
| 201821 | Ishikawa T, McNeeley S, Steiner PM, Glueck CJ, Mellies M, Gartside PS, McMillin C: Effects of chlorinated hydrocarbon on plasma alpha-lipoprotein in rats. Metabolism. 1978 Jan;27(1):89-96. Ten chlorinated hydrocarbons (tetradifon, Chlorobenzilate, Kepone, lindane, Kelthane, toxaphene, dieldrin, hexachlorobenzene, dienochlor, and Aroclor 1254; see below) were evaluated in rats to assess agents which might selectively elevate high-density lipoprotein cholesterol (C-HDL). The hepatic microsomal cytochrome P-450 content of animals receiving Aroclor, dieldrin, and Kepone was 67%, 56%, and 44% higher than control values (p less than 0.02), indicating probable hepatic enzyme induction. |
1(0,0,0,1) | Details |